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This study found that combination therapy with diphenylcyclopropenone and anthralin was more effective for complete hair regrowth in chronic extensive alopecia areata than diphenylcyclopropenone alone, despite more common side effects.

This study found that topical DPCP was more effective for hair regrowth in resistant alopecia areata compared to anthralin, with both treatments having similar safety profiles.

This overview describes the Dermatologic Surgery journal's extensive coverage of cosmetic and reconstructive skin surgery, but it reports no new research findings.

Substance P helps restore skin thickness and cell renewal when sensory nerves are reduced.

This study found that injecting PRP gel derived from a patient's own blood may promote tissue regeneration and closure of intestinal fistulas unresponsive to conservative therapy.

This study reports that a new boron/nitrogen-doped carbon nano-onion-based delivery system for doxorubicin enhanced its uptake and anticancer effects in specific cancer cell types, while reducing cardiotoxicity in human heart cells.

In this study, researchers observed that applying negative pressure to nude mice led to a significant increase in hair follicle growth and angiogenesis, suggesting potential for hair regeneration through mechanisms involving SOX-9, LHX-2, and β-catenin mediation.

This study found that the combination of TTNPB and CHIR99021 enhanced the derivation of highly advanced neural stem cells from human pluripotent stem cells, with improved chromatin accessibility and neuroectodermal gene expression, and these cells successfully engrafted in rat hippocampi to ameliorate depression-like symptoms.

Blocking a protein called prostaglandin D2 might help treat hair loss.

In this study, 12-Chloracetyl-PPD showed anti-cancer activity by inhibiting cancer cell viability and inducing apoptosis through reactive oxygen species production without harming normal cells.

This study found that three treatments with the 810-nm diode laser improved skin texture and roughness/bumpiness in keratosis pilaris patients, although it did not reduce redness.

This study found that DrugNet, a network-based prioritization method, effectively improves drug repositioning tasks, achieving high performance in validation tests and clinical trial comparisons.

This study found that DPP4 is significantly involved in matrix deposition and fibrosis in human skin fibroblasts, although the exact functions of DPP4 remain unclear.

This study shows that NIPP1 deficiency in mouse epidermis leads to hyperproliferation, hair loss, and chronic skin inflammation, which can be partially alleviated by dexamethasone treatment.

This study found that inhibiting the PI3Kδ enzyme in murine models of cutaneous chronic graft-versus-host disease (cGVHD) reduced skin scores and fibrosis, prevented pathogenic lymphoid structures, and improved survival, suggesting it as a promising therapeutic approach to address the disease's hypoxic pathophysiology.

Microneedling improves the appearance and feel of post-burn scars.

In this study, ginsenoside 20(S)-protopanaxadiol-aglycone (PPD) was shown to downregulate androgen receptor expression and inhibit tumor growth in prostate cancer cells.

This study found that peanut agglutinin binding patterns after neuraminidase pretreatment can help differentiate malignant melanoma from nevocellular nevus in skin specimens.

This study used single-cell and spatial transcriptomic profiling to identify specific molecular markers in human follicular dermal papilla cells, enhancing understanding of their role in hair follicle development.

Platelet-rich plasma with microneedling is effective for hair loss, but the number of sessions needed varies.

This study found that the antimicrobial peptide DPK-060 effectively reduced bacterial counts of Staphylococcus aureus and was safe for topical use in preclinical models, although nanocarrier encapsulation did not enhance its efficacy.

This research reviews the roles of dermal papilla signaling in hair follicle development and suggests new genetic tools could advance bioengineering therapies for alopecia, but it reports no new results.

This study found that 808 nm laser photobiomodulation altered mitochondrial respiration and enhanced osteogenic protein expression in human dental pulp stem cells, with the effects being dose-specific and more pronounced at 15 J/cm².

This study found that the opioid system, particularly via the delta opioid receptor, broadly regulates cutaneous mechanosensation, including touch, and suggests targeting this receptor could alleviate injury-induced mechanical hypersensitivity.

This study concluded that the KNPs@M/G microneedle system offers a promising strategy for treating radiation-induced skin injury by promoting antioxidative, anti-inflammatory, and regenerative effects.

This study found that videodermoscopy can help diagnose nailbed psoriasis by revealing distinctive hyponychial capillary patterns, which correlated with disease severity and response to treatment.

This study found that using deep plane fixation during scalp surgeries significantly reduced closure tension and allowed for increased tissue excision compared to standard techniques without fixation.

This study found that both microneedling and microneedling with platelet-rich plasma improved hair thickness and density in male pattern alopecia, but no additional benefit was observed with the addition of platelet-rich plasma.