research Effectiveness of OR-101, a Next Generation Highly Selective JAK3 Inhibitor, in a Humanized Murine Model of Alopecia Areata
OR-101 shows promise for treating alopecia areata by improving hair growth.
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research Hair Follicle Sulfotransferase Activity and Effectiveness of Oral Minoxidil in Androgenetic Alopecia
Low SULT activity in hair follicles leads to better response to oral minoxidil for hair loss.
research An Overview of Incidence and Mechanisms Promoting Weight Gain as an Adverse Effect of Oral Minoxidil Therapy for Androgenetic Alopecia
Oral minoxidil for hair loss can cause weight gain due to fluid retention.
research Chemoprevention of Smoke-Induced Alopecia in Mice by Oral Administration of L-Cystine and Vitamin B6
Taking L-cystine and vitamin B6 can prevent hair loss caused by smoke in mice.
research Anti-Invasive Effects of Minoxidil on Human Breast Cancer Cells: Combination with Ranolazine
Minoxidil and ranolazine together can reduce the spread of certain breast cancer cells.
research Dipeptidyl-Peptidase 4 (DPP4)-Positive Fibroblasts Are Responsible for Secretion of Pro-Fibrotic Matrix Proteins in Human Skin
DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.
research Nitric Oxide-Releasing Topical Therapeutic Agent for Atopic Dermatitis
SB414 may be an effective treatment for atopic dermatitis by reducing swelling and bacterial infection.
research The Effects of Biotin Supplementation on Serum and Liver Tissue Biotinidase Enzyme Activity and Alopecia in Rats Treated with Valproic Acid
Biotin supplements increased biotin levels but did not significantly prevent hair loss in rats on valproic acid.
research Serum and Liver Tissue Biotinidase Enzyme Activity in Rats Administered Valproic Acid
Valproic acid may cause hair loss by reducing biotinidase enzyme activity in rats.
research Knockout of mTOR/Akt Inhibitor REDD1 Results in Hair Cycle-Independent Dermal Adipose Expansion by Promoting Adipocyte Differentiation
Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.
research Valproic Acid and Alopecia: A Two-Edged Sword
Valproic acid can cause hair loss when taken orally but may promote hair growth when applied topically.
research Effects of CO2 Fractional Laser on Hair Growth in C57BL/6 Mice and Potential Underlying Mechanisms
CO2 fractional laser therapy may help regrow hair without scarring by affecting certain inflammatory and growth-related molecules.
research The Wound Healing of Fractional Photothermolysis Mimics Scarless Healing with Minimal Myofibroblast Activation
Fractional photothermolysis helps wounds heal with minimal scarring.
research Baicalin, A Flavonoid, Affects The Activity Of Human Dermal Papilla Cells And Promotes Anagen Induction In Mice
Baicalin helps hair grow by boosting certain cell activities and speeding up hair cycle in mice.
research Effect of Plant Worm Extract on Mouse Hair Growth
Plant worm extract speeds up hair growth in mice without side effects.
research Melatonin-Mediated Circadian Rhythm Signaling Exhibits Bidirectional Regulatory Effects on the State of Hair Follicle Stem Cells
Melatonin can help or hinder hair growth depending on the dose.
research Stimulation of Melanogenesis by Carthamus Tinctorius Floret Extract in B16F10 Murine Melanoma Cells
Safflower extract increases melanin production in certain skin cells without harming them.
research Comparative Efficacy and Safety of Janus Kinase Inhibitors Used in Alopecia Areata: A Systematic Review and Meta-Analysis
Baricitinib and deuruxolitinib are effective for treating alopecia areata, but their efficacy depends on the dose.
research Multiple Sclerosis: Side Effects of Interferon Beta Therapy and Their Management
The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.
research Inhibition of the Androgen Receptor by Antisense Oligonucleotides Regulates the Biological Activity of Androgens in SZ95 Sebocytes
Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.
research Experimental Study on the Effects of Ginseng Radix et Rhizoma Extract on Hair Growth in C57BL/6J Mice
Ginseng extract promoted hair growth in mice and improved local blood flow.
research In-Vitro Effect of Sex Steroids on Mouse Melanoma (B16F10) Cell Growth
Sex steroids, especially progesterone, can slow down the growth of mouse melanoma cells.
research In Vitro and In Vivo Hair Growth Promotion Effects of Lactobacillus Plantarum-Fermented Plant Extracts (MBN)
Lactobacillus plantarum-fermented plant extracts promote hair growth and thickness.
research Mobilizing Transit-Amplifying Cell-Derived Ectopic Progenitors Prevents Hair Loss from Chemotherapy or Radiation Therapy
Activating certain hair follicle cells could prevent hair loss from cancer treatments.
research Developmental Toxicity of Levo-Alpha-Acetylmethadol (LAAM) in Tolerant Rats
LAAM caused developmental toxicity in tolerant rats without causing birth defects.
research Morpho-Regulation in Diverse Chicken Feather Formation: Integrating Branching Modules and Sex Hormone-Dependent Morpho-Regulatory Modules
Sex hormones, especially estradiol, can change chicken feather shapes and colors.
research Induction of Cellular Senescence and Hair Follicle Stem Cell Dysfunction Upon p14ARF and p16Ink4a Expression in the Skin
p14ARF and p16Ink4a cause hair follicle stem cell aging and dysfunction.
research Saturable Binding of Finasteride to Steroid 5α-Reductase as Determinant of Nonlinear Pharmacokinetics
Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.
research Impact of Clinical Response on Different Approved Doses in Japan and the United States
Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.
research Chronic Toxicity of 3,4,3′,4′-Tetrachlorobiphenyl in the Marmoset Monkey (Callithrix Jacchus)
High doses of TCB cause severe health issues in marmoset monkeys.