48 citations,
May 1991 in “The journal of investigative dermatology/Journal of investigative dermatology” Trichohyalin is also found in the outer layers of normal human skin.
45 citations,
April 2016 in “Journal of Dermatological Science” The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
41 citations,
November 2013 in “Experimental Dermatology” Leptin, a hormone, is important for starting hair growth.
41 citations,
March 1992 in “Archives of Dermatology” The review suggests that understanding and treating the psychological aspect of skin disorders is important and calls for more collaboration in this field.
36 citations,
January 2010 in “Human & experimental toxicology” Eating paradise nuts led to selenium poisoning, causing nausea, hair loss, and other symptoms in two women.
35 citations,
January 2013 in “The Journal of experimental medicine/The journal of experimental medicine” CD98hc's role in skin health decreases with age.
34 citations,
November 2010 in “Development” Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
33 citations,
February 2016 in “Journal of Experimental Botany” ROOT HAIR SPECIFIC 10 (RHS10) reduces the length of root hairs in Arabidopsis plants.
32 citations,
February 2008 in “Journal of the American Academy of Dermatology” KFSD is a genetic disorder causing hair loss and skin issues, with no effective treatment.
30 citations,
September 2003 in “Experimental Dermatology” Minoxidil helps prevent stress-caused hair loss in mice.
29 citations,
March 2001 in “Clinics in Dermatology” Steven Kossard classified lymphocyte-related hair loss into four patterns, each linked to different types of baldness.
28 citations,
December 2018 in “Plant, cell & environment/Plant, cell and environment” A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.
28 citations,
January 2011 in “Hearing Research” Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.
28 citations,
March 2010 in “Histochemistry and Cell Biology” Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.
27 citations,
September 2014 in “JAMA dermatology” Female donor to male recipient sex mismatch and positive ACA-IgG are key risk factors for vitiligo and alopecia areata in chronic GvHD patients.
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August 2006 in “Laboratory Investigation” SCF and ET-1 together significantly increase skin pigmentation and melanin production.
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May 2013 in “Marine Drugs” Ishige sinicola, a type of seaweed, may help hair grow by blocking a hair loss-related enzyme and boosting important cell growth.
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November 2013 in “Journal of the American Academy of Dermatology” Many patients on new leukemia drugs had mild to moderate skin reactions.
23 citations,
December 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Finasteride works better for baldness in people with shorter gene repeats.
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December 2016 in “PloS one” A specific protein in chicken embryos links early skin layers to feather development.
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May 2011 in “American Journal of Clinical Dermatology” Recognizing and managing skin-related psychiatric disorders in children is crucial for effective treatment.
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August 2014 in “Gynecological Endocrinology” Higher hs-CRP levels in Indian adolescent women with PCOS are more related to BMI than PCOS itself.
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March 2006 in “Seminars in Cutaneous Medicine and Surgery” Minoxidil and finasteride can help with hair loss, but more research is needed to improve treatments for certain types of hair loss.
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August 2020 in “Gastroenterology report” There is no standard treatment for the rare Cronkhite–Canada syndrome, which can be fatal and lead to cancer.
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March 2019 in “Behavioural Brain Research” Finasteride use can cause depression-like behavior in male rats.
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March 2018 in “Journal of Investigative Dermatology” The gene Msx2 is crucial for hair follicle regeneration during wound healing.
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November 2017 in “Journal of Pharmaceutical Sciences” A new gel containing minoxidil can treat hair loss effectively, potentially reducing side effects and improving treatment.
18 citations,
June 2017 in “Proceedings of the National Academy of Sciences of the United States of America” A gene called Gk5 controls lipid production in the skin and affects hair growth.
18 citations,
July 2011 in “Journal of The American Academy of Dermatology” Familial factors affect hair loss types in Koreans, with M type in men, L type in women, and paternal factors influencing male hair loss more.
17 citations,
August 2012 in “Archives of Pharmacal Research” Acankoreoside J from Acanthopanax koreanum may help promote hair growth.