Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This article reviews the role of epithelial-mesenchymal interactions in hair follicle morphogenesis and the hair cycle, suggesting potential paths for developing treatments for hair growth disorders but providing no new clinical findings.

This review discusses various skin lesions associated with endocrinologic disorders such as Cushing's syndrome and adrenal insufficiency, and it reports no new clinical results.

This study found that most pathogenic HR mutants associated with atrichia with papular lesions had abolished corepressor activity due to defective interactions with histone deacetylases.

Understanding how our bodies interact with mosquito-borne viruses is crucial because there are few treatments and vaccines.

This review discusses existing forensic DNA phenotyping panels for biogeographical ancestry and externally visible characteristics and highlights major technical limitations, including terminology issues, genetic knowledge gaps, and technological debates; it reports no new results.

This review highlights how the development of forensic DNA phenotyping systems like IrisPlex, HIrisPlex, and HIrisPlex-S has advanced criminal investigation by accurately predicting physical traits such as eye, hair, and skin color from DNA, thereby improving the precision and relevance of forensic applications.

This study found that the protein p63 requires morphogenetic signals to regulate gene expression effectively during skin cell differentiation, highlighting its complex role in therapeutic reprogramming for conditions like epidermolysis bullosa.

In this study, the combination of SCF and ET-1 was found to significantly enhance skin pigmentation and melanin content in human skin xenografts on SCID mice compared to either treatment alone.

This article reviews the genetic mutations associated with hypohidrotic ectodermal dysplasia and reports no new clinical results; the authors highlight the roles of EDA gene isoforms and related receptors.

This study found that MDA-modified DNA may contribute to immune responses in alopecia areata patients by creating neo-epitopes, providing new insights into the condition's immunological mechanisms.

This study developed molecular signatures for dermal papilla cells and their niche, uncovering novel signaling regulators and genes linked to hair disorders, which may inform future hair development research.

This research found that feather pattern formation in birds is regulated by a mechanochemical system involving fibroblast growth factor and bone morphogenetic protein signaling, which is altered in the flightless emu and ostrich.

This study found that a genetic test using 5 to 20 SNPs can predict male pattern baldness with variable accuracy in European men, especially those aged 50 and older.

In this study, pantothenic acid at 20 μg/ml was observed to promote dermal papilla cell proliferation and migration, likely through up-regulation of ID3 and inhibition of Notch signaling.

This in-silico study found that Finasteride interferes with neurotransmitters and may increase psychopathology when it decomposes into a carboxylic acid similar to Cortisol.

This study explored the role of nine specific miRNAs in human hair follicles, revealing significant miRNA/mRNA correlations for miR-24, miR-31, and miR-106a and identifying target genes involved in hair biology.

This review details the adverse effects and drug interactions of biologic agents used in rheumatoid disease treatment, highlighting their significant side effect profile without reporting new clinical findings.

In this study, researchers found that interaction between transcription factor EBF1 and gene WNT10A, influenced by a genetic variant, may play a role in hair shaft formation and anagen shortening in male pattern baldness.

This study found that follistatin and activin interactions are important for hair follicle development and cycling in mice, suggesting that they may regulate processes involving BMP-2 and its antagonist.

This review discusses how macro-environmental factors such as intradermal adipose tissue and sex hormones influence hair and feather stem cell niches, suggesting environmental targets for regenerative medicine, but reports no new clinical results.

This study found that specific DNA variants in the TCHH, WNT10A, and FRAS1 genes are associated with predicting straight hair in Europeans, showing high sensitivity but low specificity, especially using a neural networks approach.

This study found that Celsr1, not Celsr2, is the primary protein involved in establishing planar cell polarity and hair follicle polarization in the epidermis of mice.

This abstract discusses the role of advanced glycation end-products in aging-related skin damage, but does not provide new findings on their impact on alopecia.

This review discusses the role of flavonoids and Nod factors in the symbiosis between legumes and rhizobia and reports no new results; the authors argue this knowledge could enhance sustainable agriculture.

This study found that lower expression of Septin4 is significantly associated with worse outcomes in colon cancer, and its interaction with BAX in DOX treatment suggests its potential in targeted therapy.

This study suggests that bioactives like Curcumin, Quercetin, and "Tulsi" may relieve chemotherapy-induced adverse drug reactions in cancer patients, potentially reducing resistance and recurrence.

In this study, researchers observed that dormant TRP-2+ melanoma cells in bone marrow can interact with CD8+ T cells in tumor-bearing ret transgenic mice, potentially influencing immune responses.

This study found that dutasteride completely suppressed the formation of 5alpha-dihydro metabolites in cultured human skin cells, suggesting its potential use in acne and androgenetic alopecia.

This study identified 417 genes with differential expression at varying stages of cashmere growth in goats, highlighting their potential role in tissue remodeling and cashmere regeneration.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.