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Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Polymeric nanoparticles show promise for treating skin diseases.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Dermatoscopy is useful for identifying different hair and scalp conditions and can reduce the need for biopsies.

Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.