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This study found that in laboratory settings, dermal papilla cells cultured as spheroids showed significantly higher hair inductive potential and angiogenic factor expression compared to monolayer cultures.

This study suggests that epithelial-derived Pop-Up Keratinocytes (ePUKs) may be a promising cell source for regenerative medicine due to their specific phenotypic traits and their influence on wound healing.

This study found that Hedgehog-driven skin tumorigenesis is dependent on the Wnt/beta-catenin signaling pathway and suggests that targeting Wnt ligands could be a potential therapeutic strategy.

This study concluded that S. hexaphylla extract may improve androgenetic alopecia by reducing 5α-reductase and androgen receptor levels, inhibiting apoptosis, and promoting keratinocyte proliferation in experimental models.

This study suggests that inaudible sound at 30 kHz may promote hair growth and inhibit hair loss signals in human dermal papilla cells, indicating potential as a new treatment for androgenic alopecia.

This study found that injection of adipose-derived adult stem cells improved hair density, thickness, and reduced inflammation in women with female pattern hair loss over 24 weeks.

This study found that intradermal injection of a cell-penetrating, AR-targeting asiRNA promoted hair growth and reduced androgen receptor expression in mouse models of androgenetic alopecia, suggesting its therapeutic potential.

This study suggests that elevated DKK1 expression, influenced by promoter methylation, is a significant prognostic biomarker for patients with head and neck squamous cell carcinoma.

In this study, treatment with recombinant DKK2 was shown to significantly stimulate hair progenitor cell growth and enhance hair shaft elongation in ex vivo human hair follicle cultures by activating the Wnt/ẞ-catenin signaling pathway, suggesting a potential role for DKK2 in promoting hair growth.

This article reviews the role of Kremen proteins as regulators in the Wnt/β-catenin signaling pathway, highlighting their significance in development and cancer, but reports no new clinical results.

This study found that Wnt signaling is crucial for bone regeneration, as inhibiting it drastically reduced bone repair in mice, while constitutive activation delayed regeneration by keeping cells in a proliferative state.

This study found that Wnt10a expression in odontoblasts increased with dental pulp regeneration and may be a potential non-cellular agent for inducing dental pulp regeneration with dentine-inducing capacity.

In this study, applying water extracts of liquorice at a concentration of 2.5% to male rabbits led to the best rate of hair growth at 2.19 cm over 35 days, while a 5% concentration resulted in the greatest hair weight at 0.12 grams.

This review discusses the multiple layers of environmental controls on hair stem cell homeostasis and suggests that targeting these layers could offer safer regenerative medicine therapies without directly using stem cells.

This study identified a unique transcriptional signature in occipital hair follicles that may protect them from miniaturization in androgenetic alopecia, using an animal-free model to investigate gene roles.

This study found that morroniside enhanced hair follicle growth and transition through the Wnt/β-catenin signaling pathway in a mouse model, suggesting its potential as a treatment for hair loss.

Skin-derived stem cells could help treat skin aging and pigmentation issues.

This review introduces the morphological and molecular principles of hair follicle development but reports no new experimental results, focusing on recent insights and forming a working hypothesis.

This review discusses the molecular mechanisms of androgens and androgen receptors in skin disorders, particularly androgenetic alopecia, and reports no new clinical results; it highlights potential areas for future treatment development.

This review discusses the dual role of the Wnt/β-catenin pathway in mammalian tissue injury, highlighting its potential for both promoting regeneration and contributing to fibrosis, but presents no new findings.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

This study found that overexpression of Wnt1a in bone marrow mesenchymal stem cells enhanced mouse hair follicle regeneration and promoted hair cycling.

This study found that Puerariae Flos extract inhibited testosterone 5α-reductase and promoted hair growth in mouse models, suggesting its potential use for treating androgenic alopecia.

This study found that collagen VI influences hair follicle growth and wound-induced regrowth by activating the Wnt/β-catenin signaling pathway in mice, suggesting potential therapeutic targets for hair loss.

In this study, microneedles combined with finasteride nanostructured lipid carriers (FIN-NLC-MNs) were found to enhance skin penetration and specifically target hair follicles, promoting hair growth and gene regulation in androgenetic alopecia.

This review introduces an integrated view of hair follicle behavior, highlighting a Yin Yang model of regulation and suggesting glycans as key elements in hair follicle growth control, without reporting new clinical findings.

This study identified overexpression of certain immune-related genes and underexpression of genes in specific signaling pathways in premature androgenetic alopecia, suggesting potential new therapeutic targets.

Sfrp2 increases during hair follicle catagen phase and slows keratinocyte growth.

This study suggests that mesenchymal stem cell therapy may improve cell viability and regulate key signaling pathways in vitro for treating alopecia areata.

This study found that combining platelet-rich plasma therapy with minoxidil was more effective in treating androgenetic alopecia in men than either treatment alone.