research An Open-Label Pilot Clinical Trial of the JAK Inhibitor Tofacitinib for Alopecia Areata
Tofacitinib, a JAK inhibitor, improved hair regrowth in most patients with severe alopecia areata and had minimal side effects.
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450-480 / 1000+ results research Phospholipase A2 in Skin Biology: New Insights from Gene-Manipulated Mice and Lipidomics
Phospholipase A2 enzymes play key roles in skin health and disease.
research Editorial: Machine Learning Techniques on Gene Function Prediction Volume II
Machine learning is effective in predicting gene functions and their relationships with diseases.
research Current Management Strategies for Cutaneous T-Cell Lymphoma
The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.
research Face Transplantation for Granulomatosis With Polyangiitis (Wegener Granulomatosis)
Face transplant for a severe autoimmune disease patient was successful, improving appearance and function without disease relapse after three years.
research Thiopurines: Recent Topics and Their Role in the Treatment of Inflammatory Bowel Diseases
Thiopurines help treat IBD but require genetic testing to avoid side effects.
research Free Testosterone Levels in Patients with COVID-19 and Its Association with Disease Severity
People with lower levels of free testosterone tend to have worse COVID-19 outcomes.
research Human Leukocyte Antigen Class II Alleles Are Associated with Risk of Alopecia Areata
Certain HLA class II alleles increase or decrease the risk of alopecia areata.
research Salvage Therapy for Prostate Cancer: AUA/ASTRO/SUO Guideline Part II: Treatment Delivery for Non-Metastatic Biochemical Recurrence After Primary Radical Prostatectomy
Adding hormone therapy to radiation improves survival for high-risk prostate cancer recurrence but has side effects.
research Aesthetics in Psychosomatic Dermatology II: Skin Changes Experienced as Cutaneous Disease
People distressed by minor skin changes should consult dermatologists with cosmetic expertise, and a public Cosmetic Dermatology Service with mental health support is recommended.
research Skin Surgery: Volumes I and II
The document suggests improvements for a hair and scalp disease book and recommends a two-volume skin surgery reference for dermatologists.
research Plasticity of Differentiated Cells in Wound Repair and Tumorigenesis, Part II: Skin and Intestine
Mature cells can re-enter the cell cycle and potentially lead to cancer.
research Finasteride Induces Epigenetic Alteration of TMPRSS2 Gene Expression: A Potential Role in Severe Acute Respiratory Syndrome Coronavirus 2 Inhibition
Finasteride may help reduce COVID-19 infection by altering a key gene.
research Phase II Evaluation of VDC-1101 in Canine Cutaneous T-Cell Lymphoma
VDC-1101 shows potential as a treatment for canine cutaneous T-cell lymphoma.
research Comment on: The Gabrin Sign
The document suggests that more research is needed to confirm if baldness can indicate a higher risk of severe COVID-19 in men.
research Computer-Assisted Epitope Prediction Revealed Potential Autoantigens Associated with Human Alopecia Areata
Melanogenesis-related proteins may trigger immune responses in alopecia areata patients.
research Cocaine-Related Bullous Disease
Cocaine use can cause a blistering skin disease.
research Types I and II Keratin Intermediate Filaments
Keratins are crucial for cell structure, growth, and disease risk.
research Type II Vitamin D Dependent Rickets: A Case Report
Hair loss can be a key sign of a rare type of rickets when vitamin D treatment doesn't work and advanced tests aren't available.
research Keratins: Dynamic, Flexible Structural Proteins of Epithelial Cells
Keratin proteins in epithelial cells are dynamic and crucial for cell processes and disease understanding.
research Disease Prevention and Alleviation by Human Myoblast Transplantation
Myoblast transplantation shows promise for treating various muscle and heart conditions.
research Ectodysplasin Research: Where to Next?
Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.
research A Study of Patterns of Androgenetic Alopecia in Men: An Indian Perspective
Indian men have 62.1% hair loss, mostly grade II vertex, and less extensive than other populations.
research The Use of Oral Recombinant Feline Interferon Omega in Two Cats with Type II Diabetes Mellitus and Concurrent Feline Chronic Gingivostomatitis Syndrome
Oral feline interferon-omega improved symptoms in diabetic cats with gingivostomatitis.
research Self-Reported Alopecia in an Ethnically Diverse Lupus Cohort
Alopecia is common in lupus patients, causing significant anxiety and is linked to the disease itself.
research Postural Orthostatic Tachycardia Syndrome: A Dermatologic Perspective and Successful Treatment with Losartan
Losartan may help treat Postural Orthostatic Tachycardia Syndrome (POTS) symptoms.
research Clinical and Histological Challenge in the Differential Diagnosis of Diffuse Alopecia: Female Androgenetic Alopecia, Telogen Effluvium, and Alopecia Areata – Part II
Diagnosing diffuse alopecia, a hair loss condition, can be challenging and may require a scalp biopsy or tracking the disease's progression when symptoms and skin tests aren't enough.
research Multiple Autoimmune Syndrome Type 3: Thyroiditis, Vitiligo, and Alopecia Areata
A woman with multiple autoimmune diseases showed improvement in hair loss but not in skin discoloration after treatment.
research Safety and Efficacy of Advanced and Targeted Acid α-Glucosidase (AT-GAA) (ATB200/AT2221) in ERT-Switch Nonambulatory Patients with Pompe Disease: Preliminary Results from the ATB200-02 Trial
The combination of tadalafil and finasteride improves urinary symptoms and erectile function in men with enlarged prostates.
research Research Snippets: Dermatological Genetics and Conditions
New gene mutations linked to skin conditions were found, bacteria and chemicals may worsen acne, a dog mutation could exist in humans, virus-like elements might be involved in psoriasis, and a vitamin D3 treatment doesn't prevent chemotherapy-related hair loss.