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TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Forming spheres boosts the ability of certain human cells to create hair follicles when mixed with mouse skin cells.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Cepharanthine, a Japanese hair loss drug, shows promise as a COVID-19 treatment but needs more testing.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Certain drugs that block specific enzymes can help treat prostate diseases.

Researchers found a new way to create hair-growing structures in the lab that can grow hair when put into mice.

Surface Plasmon Resonance is a useful tool for studying protein interactions and has potential for future technological advancements.

Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Genetic and environmental factors, like smoking and exercise, affect male hair loss.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Dihydrotestosterone increases certain inflammatory signals in skin cells, potentially contributing to acne.

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.

Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.

Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.

New methods like nanoparticles and microneedles show promise for better skin drug delivery, especially for hair disorders.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Hair follicle culture helps develop new treatments for hair loss.