research Follicular Delivery of Spironolactone via Nanostructured Lipid Carriers for Management of Alopecia
Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.
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research Factors Associated with Anti-SARS-CoV-2 IgG Antibody Production in Patients Convalescing from COVID-19
Men, diabetes, and high inflammation levels lead to higher COVID-19 antibodies.
research The Good, the Bad, and the Ugly Facets of Insulin Resistance
Insulin resistance is a complex condition that can lead to many diseases and has few treatment options.
research Dicer- and Bulge Stem Cell-Dependent MicroRNAs During Induced Anagen Hair Follicle Development
MicroRNAs are important for hair growth regulation, with Dicer being crucial and Tarbp2 less significant.
research Cell-Free Fat Extract Restores Hair Loss: A Novel Therapeutic Strategy for Androgenetic Alopecia
A substance called Cell-free fat extract can effectively treat common hair loss by increasing hair growth and density.
research Alopecia Areata: Diagnostic and Therapeutic Recommendations of the Polish Society of Dermatology. Part 2: Treatment
The Polish Society of Dermatology recommends treatments for alopecia areata that vary by severity, including topical and systemic medications, with long-term maintenance important for management.
research A Systematic Review on Clinical Evidence for Topical Metformin: Old Medication With New Application
Topical metformin shows promise for dental and skin treatments, including periodontitis, hair regrowth, wound healing, and acne.
research Innate Immunity Activation of Sebocyte Cells by Living Bacteria: Evidence of a Potential Immunosuppressive Effect of DHT
DHT may reduce inflammation caused by certain bacteria in skin cells.
research Myotonic Dystrophy Type 1: Enhancing Patient Management Through Genetic and Multisystem Studies
There is no cure for myotonic dystrophy type 1, so treatment focuses on managing symptoms and complications.
research Sarcoidosis: Are There Differences in Your Skin of Color Patients?
Sarcoidosis is more common and severe in Black patients than in Caucasians, requiring early diagnosis and treatment.
research A Spontaneous Deletion Within the Desmoglein 3 Extracellular Domain of Mice Results in Hypomorphic Protein Expression, Immunodeficiency, and a Wasting Disease Phenotype
A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.
research Spherical Nucleic Acids as Emerging Topical Therapeutics: A Focus on Psoriasis
New topical treatment using spherical nucleic acids shows promise in reducing psoriasis inflammation.
research Antiviral Drugs Prolong Survival in Murine Recessive Dystrophic Epidermolysis Bullosa
Antiviral drugs, especially daclatasvir, may be a new treatment for a rare skin disease, improving survival and reducing symptoms in mice.
research Interventions for Morphea
Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.
research Alopecia Areata Patients Show Deficiency of FOXP3+CD39+ T Regulatory Cells and Clonotypic Restriction of Treg TCRβ-Chain, Highlighting the Immunopathological Aspect of the Disease
Patients with Alopecia areata have fewer specific immune cells that normally regulate the immune system, which may contribute to the condition.
research A Humanized Mouse Model of Hereditary 1,25-Dihydroxyvitamin D–Resistant Rickets Without Alopecia
Researchers created a mouse model of a type of rickets that does not cause hair loss.
research Targeting Anti-Inflammatory Immunonanocarriers to Human and Murine Neutrophils via Ly6 Antigen for Psoriasiform Dermatitis Alleviation
The study created special nanoparticles that effectively deliver an anti-inflammatory drug to treat skin inflammation in psoriasis.
research Abstracts From The 55th European Society Of Human Genetics Conference: E-Posters
Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.
research Niosomal And Ethosomal Gels: A Comparative In Vitro And Ex Vivo Evaluation For Repurposing Of Spironolactone
Niosomes and ethosomes can effectively carry the drug spironolactone, potentially improving treatment for hair loss and reducing side effects.
research Anti-Androgenic Therapy with Finasteride Improves Cardiac Function, Attenuates Remodeling, and Reverts Pathologic Gene Expression After Myocardial Infarction in Mice
Finasteride improves heart function and repairs damage after heart attack in mice.
research Factors Predicting Response to Oral Methylprednisolone Tapering Treatment in Alopecia Areata: A Retrospective Study
Younger patients and those with more hair loss are less likely to benefit from oral steroid treatment for hair loss, and low vitamin D may predict relapse.
research APCDD1 Is a Novel Wnt Inhibitor Mutated in Hereditary Hypotrichosis Simplex
A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
research Development of Finasteride Polymer Microspheres for Systemic Application in Androgenic Alopecia
Finasteride microspheres help reduce hair loss for up to eight weeks with fewer side effects.
research DNA Damage Response Mediates Pressure Overload-Induced Cardiomyocyte Hypertrophy
Targeting ATM could help manage heart cell enlargement due to pressure overload.
research Whole Exome Sequencing in Alopecia Areata Identifies Rare Variants in KRT82
Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.
research BH07: Testosterone Deficiency in Men with Female Pattern Hair Loss
Low testosterone levels may contribute to female pattern hair loss in men.
research Novel Micelle Formulations to Increase Cutaneous Bioavailability of Azole Antifungals
New micelle solutions greatly improve skin delivery of certain antifungal drugs.
research Comprehensive Overview of Hidradenitis Suppurativa
The document concludes that lifestyle changes and medical treatments can significantly reduce symptoms of Hidradenitis Suppurativa, a chronic skin condition.
research Alopecia Areata But Not Androgenetic Alopecia Is Characterized By A Restricted And Oligoclonal T-Cell Receptor-Repertoire Among Infiltrating Lymphocytes
Alopecia areata involves specific T-cells, unlike androgenetic alopecia.
research Hidradenitis Suppurativa: A Comparison of Guidelines
There is no gold standard treatment for hidradenitis suppurativa due to insufficient evidence.