27 citations,
September 1999 in “Journal of Investigative Dermatology” Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.
25 citations,
May 1994 in “Journal of Investigative Dermatology” Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.
24 citations,
July 1983 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by blocking male sex hormones.
14 citations,
April 2011 in “Journal of the American Academy of Dermatology” Researchers found a gene mutation responsible for a rare hair loss condition.
14 citations,
January 2004 in “Journal of Biochemical and Molecular Toxicology” Mustard gas exposure causes hair loss, but treating with N-acetylcysteine can prevent it.
12 citations,
January 2016 in “Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie” Researchers found a new mutation in the EDA gene that likely causes missing teeth and mild skin symptoms in one family.
9 citations,
August 2013 in “Archives of Dermatological Research” A gene called BMAL1 plays a role in controlling hair growth.
8 citations,
January 2012 in “JIMD reports” A new mutation in the AGPAT2 gene causes severe fat tissue loss and related health issues by reducing the protein's levels.
6 citations,
October 2013 in “Plastic and Reconstructive Surgery – Global Open” HSL treatment speeds up hair growth and reduces oxidative stress in hair follicles of ob/ob mice.
6 citations,
December 2011 in “Nature” The circadian clock in skin cells controls their growth and rest cycles.
4 citations,
January 2011 in “Annals of Dermatology” Researchers found a new mutation in the HR gene linked to a rare hair loss condition.
4 citations,
November 1968 in “Textile research journal” Hair fibers may have a unique, non-protein sheath not previously identified.
3 citations,
November 2005 in “Dermatologic Surgery” Aminoguanidine increases a specific growth signal in stored hair grafts, which may help them survive better after being transplanted.
2 citations,
July 2015 in “Archives of Dermatological Research” A new gene variant in the DSP gene is linked to a unique type of hair loss.
2 citations,
June 2003 in “International Journal of Acarology” Researchers found a new mite species causing severe hair loss and skin problems in yellow-bellied marmots.
1 citations,
November 2005 in “Dermatologic Surgery” Aminoguanidine increases VEGF in stored hair micrografts, potentially improving their viability after transplant.
July 2024 in “New Phytologist” PDF2 senses specific lipids and regulates root growth and gene expression in Arabidopsis.
January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The gp130 receptor helps in tissue regeneration and disease progression, and manipulating it could improve healing and prevent disease.
Activin A increases inner ear hair cell development, while follistatin decreases it.
April 2019 in “Journal of Investigative Dermatology” Activating the Sonic hedgehog pathway can help regenerate hair follicles during wound healing in mice, potentially improving regeneration after injury.
September 2018 in “Practical diabetes” Sodium valproate is not recommended as a first-line treatment for neuropathy but may be used in resistant cases.
August 2016 in “Journal of Investigative Dermatology” Researchers found a new genetic mutation linked to a hair condition in a Japanese boy.
June 2014 in “British Journal of Dermatology” Eczema patients have a lower skin lipid to protein ratio, older and longer-staying hospital patients are more likely to get pressure ulcers, hair loss in AGA is linked to muscle degeneration, vitamin D deficiency is common in alopecia areata and linked to its severity, standard liver tests don't effectively detect fibrosis in psoriasis patients on methotrexate, and bullous pemphigoid patients have a higher death risk but combination therapy may reduce it.
January 1983 in “Elsevier eBooks” Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.
171 citations,
July 2007 in “Journal of Investigative Dermatology” A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
130 citations,
May 1988 in “Journal of The American Academy of Dermatology” "Male-pattern" hair loss is common in women, especially after menopause, and doesn't always mean there's a problem with hormone balance.
82 citations,
August 2017 in “Cell Reports” An imbalanced gut and lack of biotin can cause hair loss in mice.
64 citations,
January 2010 in “The FASEB Journal” Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.
40 citations,
January 1994 in “Skin Pharmacology and Physiology” Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.
29 citations,
January 2017 in “Journal of Investigative Dermatology” The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.