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Minoxidil's effectiveness decreases as vehicle evaporates; concentration and thermodynamic activity matter.

Different hair protein amounts change the strength of keratin/chitosan gels, useful for making predictable tissue engineering materials.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.

Iron deficiency may contribute to hair loss.

New sensor detects minoxidil accurately and effectively.

Dermoscopy is useful for diagnosing various skin, hair, and nail disorders and can reduce the need for biopsies.

PRP treatment improves hair density and thickness for alopecia, but needs more research.

Microneedles with enhancer effectively promote hair growth and increase hair density.

Low-level laser therapy effectively treats female hair loss, increasing hair count by 51%.

Using finasteride or dutasteride does not increase the risk of male breast cancer.

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.

Where melanoma is on the body affects survival chances; melanomas on the back of the head are worse, while those on thighs and arms are less severe, and more sun exposure might improve survival.

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.

Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.

Iontophoresis improves minoxidil delivery to hair follicles for hair loss treatment.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

NF-κB is crucial for different stages and types of hair growth in mice.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.

Nano-sized lipid particles increase dexamethasone's skin penetration and create a reservoir in the skin layers.

Modified keratin binds better to hair, especially bleached hair.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.