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In this case report, researchers document a female dog in tropical conditions with dermatophytosis, a zoonotic fungal infection common in hot and humid climates, showing symptoms like alopecia on the neck and ear tips.

This report describes a case of dermatophytosis, a zoonotic fungal infection common in tropical and temperate climates, affecting a female dog with alopecia on its neck and ear tip.

Pharmacists play a crucial role in patient care and education.

This study found that tideglusib delivered topically in a bacterial cellulose hydrogel showed positive effects on the wound healing of rat palatal mucosa, as observed through macroscopic, histomorphometric, and immunohistochemical evaluations.

This study found that microplastics on the Lebanese Mediterranean coast transport various organic and inorganic pollutants, posing threats to marine organisms and potentially human health.

This study found that the nutraceutical product DERM decreased the pro-inflammatory cytokine IL-6 in mesenchymal stem cells under in vitro conditions.

This study found that the ethanol extract of mangkokan leaf (Polyscias scutellarium) demonstrated antibacterial activity against Escherichia coli and Staphylococcus aureus, with higher concentrations showing greater inhibition zones, particularly against Staphylococcus aureus.

In this study, three patients with Type-1 autoimmune hepatitis experienced normalized liver enzymes and remission after six months of oral prednisolone treatment, while three others refused treatment.

This research focused on formulating finasteride, dutasteride, and minoxidil with cyclodextrins to enhance their solubility and skin penetration for topical use, potentially reducing scalp irritation from current alcohol-based preparations.

This article discusses vaccination coverage for BCG, Polio, and Hepatitis B in Juiz de Fora using SUS data and reports no new results; the authors aim to hypothesize reasons for coverage variation.

This review investigates the relationship between certain gene polymorphisms associated with obesity (FTO and MC4R) and Polycystic Ovarian Syndrome, reporting no new results but suggesting a potential genetic link.

This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.

This study found that the ethanolic extract of Guazuma ulmifolia, or mutamba, showed only intermediate levels of phenolic compounds and low antioxidant activity in laboratory tests, suggesting limited potential in alleviating oxidative stress conditions like cancer or cardiovascular diseases.

This study observed that unpigmented keratinocytes saturate quickly with foreign substance uptake compared to pigmented melanocytes, where melanin significantly enhances binding.

This article reviews methotrexate's pharmacokinetics and toxicity, emphasizing the role of urinary excretion and leucovorin in avoiding most toxic reactions; it provides no new clinical results.

This review discusses various strategies, including vitamin A and dextromethorphan supplementation, to manage methotrexate toxicity and improve adherence in patients with rheumatic diseases, but reports no new clinical results.

This study suggests that applying topical Tempol to the scalp before whole brain radiation may protect against radiation-induced alopecia and is safe and well-tolerated.

This communication discusses previous reports of deadly hematopoietic depression associated with the topical use of demecolcine for skin cancers, highlighting potential hazards relative to colchicine ointment in psoriasis.

This review discusses methotrexate's use in dermatology and its mechanisms, pharmacokinetics, dosing, side effects, interactions, and emphasizes the need for further research into optimizing therapy and predicting adverse events.

This study found that low-dose methotrexate significantly reduced the steroid requirement in subjects with corticosteroid-requiring asthma without altering their clinical status or causing significant complications.

This study reported that the Fe@C/CB electrocatalyst effectively detected Metol in water samples with a low detection limit, high sensitivity, and good stability, suggesting it as a promising tool for environmental monitoring.

This study evaluated the real-world safety of Tepotinib for treating NSCLC with METex14 skipping mutations, confirming known adverse events and identifying new signals like deafness and taste disorder, especially highlighting early monitoring.

This review found that tea tree oil, especially terpinen-4-ol, may be the most effective treatment for Demodex-related diseases, but more research is needed to improve treatment efficacy and reduce side effects.

This study found that nanobubble-encapsulated diclofenac with ultrasound-targeted microbubble destruction (DNBs-UTMD) can enhance the anti-tumor efficacy of Doxil® by regulating the tumor immune microenvironment, improving drug uptake, and increasing T cell responses while reducing immune-suppressive cells in the process.

The researchers developed semi-dissolving microneedle patches using TEMPO-oxidized bacterial cellulose nanofibers, which allow effective transdermal drug delivery by forming micro-channels for large drug quantities, overcoming traditional microneedles' low drug loading.

This study found that Datura metel extracts obtained through supercritical CO2 extraction demonstrated significant biological activity, including antioxidant and anti-inflammatory properties, and effectively promoted wound closure and collagen preservation, comparable to standard treatments, in laboratory experiments.

This study found that long-term weekly administration of docetaxel is feasible at doses up to 45 mg/m² per week with acceptable toxicity, and suggests further evaluation with 40 mg/m² for phase II studies.

This study found that Transcutol-containing vesicles improved the delivery of minoxidil to deeper skin layers in vitro but did not facilitate its permeation through the skin.

This study confirmed that methimazole use is associated with agranulocytosis, pyrexia, exposure during pregnancy, and hyperthyroidism, while also identifying new safety signals like premature birth and septic shock that require further investigation.

This review found no evidence supporting the efficacy of methotrexate for inducing remission in active ulcerative colitis compared to placebo or active comparators.