research Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers
Finasteride safely lowers DHT levels without affecting testosterone.
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research A Novel Finasteride 0.25% Topical Solution for Androgenetic Alopecia: Pharmacokinetics and Effects on Plasma Androgen Levels in Healthy Male Volunteers
New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.
research Effects of the Anti-Androgen Finasteride on 5α-Reduction of Androgens in the Presence of Progesterone in Human Gingival Fibroblasts: Modulatory Actions of the Alkaline Phosphatase Inhibitor Levamisole
Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.
research Effects of Camellia Oleifera Seed Shell Polyphenols and 1,3,6-Tri-O-Galloylglucose on Androgenic Alopecia via Inhibiting 5α-Reductase and Regulating Wnt/β-Catenin Pathway
Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose can help treat hair loss by reducing certain hormones and promoting hair growth.
research Effects of Taxifolin-3-O-Arabinopyranoside from Rhododendron Mucronulatum Root Extracts on the Alleviation of Hair-Loss Symptoms
The compound from Rhododendron mucronulatum roots may help treat male pattern hair loss.
research Epitestosterone: Regulatory Roles in Androgen-Dependent Processes
Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.
research Sex-Specific Difference of Hippocampal Synaptic Plasticity in Response to Sex Neurosteroids
Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
research The Effect of Administration and Discontinuation of Finasteride in Male Rats
Finasteride's negative effects on brain tissue in male rats may be reversible after stopping the drug.
research Advances in Knowledge of Androgens: How Intentional and Accidental Neurosteroid Changes Inform Us of Their Action and Role
Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
research 5-Alpha Reductase Inhibitors: New Evidence on Benefits and Harms Beyond Benign Prostatic Hyperplasia
5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.
research 5α-Reductase Inhibitors and Male Reproduction
5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.
research Finasteride in Androgenic Alopecia
Finasteride treats hair loss but may cause side effects like low libido and dizziness.
research 5-Alpha Reductase Inhibitors Use in Prostatic Disease and Beyond
5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.
research Finasteride
Finasteride effectively treats baldness but may cause sexual side effects.
research The Antiandrogenic Action of 4-Androsten-3-One-17β-Carboxylic Acid and Its Methyl Ester on Hamster Flank Organ
The chemicals 17βC and its methyl ester can block the effects of testosterone on hamster skin but not the effects of DHT.
research Spironolactone Therapy for Hyperandrogenic Anovulatory Women: Clinical and Endocrinological Study
Spironolactone improved symptoms in women with hormonal imbalances and had few side effects.
research Exploring Rat Corpus Cavernosum Alterations Induced by Finasteride Treatment and Withdrawal
Finasteride changes hormone levels and certain proteins in rats, but these effects can be reversed after stopping the drug.
research A Narrowed Look Into Plant-Derived Testosterone 5α-Reductase Inhibitors for Androgenetic Alopecia
Plant-based treatments might help with hair loss and have fewer side effects than synthetic drugs.
research Screening the Chemical Composition and Bioactivity of Cerasus Serrulata Flower Extracts Using Two Extraction Methods
Cerasus serrulata flower extracts have strong antibacterial and antioxidant effects and may help prevent hair loss.
research Novel Androgen Receptor Degrader for Androgenetic Alopecia (AGA) Application
A new treatment for hair loss shows promise with fewer side effects.
research Therapeutic Potential of Celtis Choseniana Nakai on Androgenic Alopecia Through Repression of Androgen Action and Modulation of Wnt/Beta-Catenin Signaling
Celtis choseniana may help treat hair loss by reducing androgen effects and boosting hair growth signals.
research A Review on Finasteride: A 5-Alpha Reductase Inhibitor, Its Mechanism, Facts, and Benefits
Finasteride effectively treats hair loss and prostate issues with minimal side effects.
research Gas Chromatography/Mass Spectrometry Based Hair Steroid Profiling May Reveal Pathogenesis in Hair Follicles of the Scalp
Analyzing hair with this method can help understand and monitor scalp conditions and treatment effects.
research Human Mesenchymal Stem Cell-Derived Conditioned Media for Hair Regeneration Applications
Stem cell therapy could be a promising alternative for hair regrowth with fewer side effects.
research Phytochemicals With Anti 5-Alpha-Reductase Activity: A Prospective For Prostate Cancer Treatment
Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.
research The Use of Serenoa Repens (Saw Palmetto) in Hair Care Products
Saw palmetto in hair products might reduce hair loss but can cause side effects.
research Saw Palmetto (Serenoa Repens) in Androgenic Alopecia: An Effective Phytotherapy
Saw palmetto is an effective natural treatment for hair loss with minimal side effects.
research Comparing Current Therapeutic Modalities of Androgenic Alopecia: A Literature Review of Clinical Trials
Some treatments for hereditary hair loss are effective but vary in results and side effects; new therapies show promise but need more research.
research Evaluating 5 Alpha Reductase Inhibitors for the Treatment of Male Androgenic Alopecia
Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.
research Topical Finasteride: A Comprehensive Review of Androgenetic Alopecia Management for Men and Women
Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.