research Intracrine and Myotrophic Roles of 5α-Reductase and Androgens
Muscles can make their own androgens, which may help muscle growth.
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research Hair Aging And Anti-Aging
Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.
research Moxibustion Improves Ovarian Function Based on the Regulation of the Androgen Balance
Moxibustion may help improve ovarian function by changing androgen levels.
research Female Antiandrogens: Significance, Treatment, and Environmental Concerns
Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.
research 52243 AH-001: An Emerging Androgen Receptor Degrader Showing Therapeutic Potential in Addressing Androgenetic Alopecia
AH-001 could be a safer and more effective treatment for hair loss.
research Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders
New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
research In Vitro Hair Growth-Promoting Effect of Lgr5-Binding Octapeptide in Human Primary Hair Cells
A synthetic octapeptide may help promote hair growth and counteract hair loss.
research Impact of Testosterone on Hair and Skin
Testosterone can cause acne and male-pattern baldness, affects hair growth in men and women, and makes male skin more sensitive.
research A Model for the Turnover of Dihydrotestosterone in the Presence of the Irreversible 5α-Reductase Inhibitors GI198745 and Finasteride
Both drugs lower DHT levels, with GI198745 being more effective.
research 17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells
Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.
research Inhibitory Effects of Serenoa Repens on the Kinetics of Pig Prostatic Microsomal 5α-Reductase Activity
Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
research Protective Effects of Finasteride on the Pulmonary Immune Response in a Combined Model of Trauma-Hemorrhage and Polymicrobial Sepsis in Mice
Finasteride helps reduce lung inflammation and damage after trauma and infection.
research A Curvilinear Relationship Between Hair Loss, Mental Rotation, and Neuroticism: A Possible Influence of Sustained Dihydrotestosterone Production
Men with moderate hair loss had the best spatial thinking, and long-term DHT might affect cognition.
research Adverse Effects of 5-Alpha Reductase Inhibitor Therapy in Men With Androgenetic Alopecia: Is There Cause for Concern?
5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.
research Beneficial Effects of Finasteride on Hepatic and Pulmonary Immune Response After Trauma Hemorrhage in Mice
Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.
research The Effects of Estrogens on Linear Bone Growth
Oestrogens are key for bone growth during puberty in both boys and girls.
research The Effects of Finasteride on Scalp Skin and Serum Androgen Levels in Men with Androgenetic Alopecia
Finasteride effectively reduces hair loss by decreasing androgen levels.
research The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients with Male Pattern Baldness
Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.
research Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility
PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
research Effect of Dihydrotestosterone on the Upregulation of Inflammatory Cytokines in Cultured Sebocytes
Dihydrotestosterone increases certain inflammatory signals in skin cells, potentially contributing to acne.
research Cognitive Effects of Testosterone and Finasteride Administration in Older Hypogonadal Men
Testosterone improves mood and thinking skills; finasteride has no effect.
research Effects of Oral Finasteride on Erectile Function in a Rat Model
Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.
research The Effects of Lovastatin on Conventional Medical Treatment of Lower Urinary Tract Symptoms with Finasteride
Lovastatin doesn't improve lower urinary tract symptoms treatment.
research Dihydrotestosterone-Induced Hair Regrowth Inhibition by Activating Androgen Receptor in C57BL6 Mice Simulates Androgenetic Alopecia
DHT stops hair regrowth in mice, similar to human hair loss.
research Protective Effects of Finasteride Against Testosterone-Induced Calcium Oxalate Crystallization and Crystal-Cell Adhesion
Finasteride helps prevent kidney stones, but side effects need more research.
research Effects of the Anti-Androgen Finasteride on 5-Alpha-Reductase Activity in Human Gingival Fibroblasts in Response to Minocycline
Finasteride helps treat hair loss by blocking enzyme activity.
research Sulforaphane Promotes Murine Hair Growth by Accelerating the Degradation of Dihydrotestosterone
Sulforaphane may help with hair growth by breaking down a hormone that causes hair loss.
research Preventive Effects of Monascus on Androgen-Related Diseases: Androgenetic Alopecia, Benign Prostatic Hyperplasia, and Prostate Cancer
Monascus helps prevent baldness, prostate issues, and may be a natural alternative to medications.
research The Effects of Estrogens on Linear Bone Growth
Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.
research Inhibitory Effects of Polyacetylene Compounds from Panax Ginseng on Neurotrophin Receptor-Mediated Hair Growth
Certain compounds from Panax ginseng can block proteins that affect hair growth, potentially helping treat hair loss.