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240-270 / 1000+ results![4-(Alkylthio)- and 4-(arylthio)-benzonitrile derivatives as androgen receptor antagonists for the topical suppression of sebum production](/images/research/ab9e9ee9-c857-462e-be32-1653d74b31bc/small/12604.jpg)
research 4-(Alkylthio)- and 4-(arylthio)-benzonitrile derivatives as androgen receptor antagonists for the topical suppression of sebum production
Chemicals called 4-(alkylthio)- and 4-(arylthio)-benzonitrile derivatives can potentially reduce oil production on skin, which could help treat conditions like acne and hair loss.
![Post-finasteride Syndrome: A Review of Current Literature](/images/research/8425b010-52de-4414-a459-c51dfbc47c4d/small/4339.jpg)
research Post-finasteride Syndrome: A Review of Current Literature
Post-finasteride Syndrome causes lasting negative effects, but more research is needed for treatment and risk evaluation.
![Repurposing existing drugs for COVID-19: an endocrinology perspective](/images/research/6f5e0d43-a933-4f89-bab0-75fe7d1e47b6/small/12127.jpg)
research Repurposing existing drugs for COVID-19: an endocrinology perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
![Maximum Efficacy of Finasteride Is Obtained within 6 Months and Maintained over 6 Years](/images/research/5a20e745-2839-4e52-bfff-8eb04cb9805b/small/2174.jpg)
research Maximum Efficacy of Finasteride Is Obtained within 6 Months and Maintained over 6 Years
Finasteride works best in 6 months and lasts 6 years.
![Finasteride, not tamsulosin, increases severity of erectile dysfunction and decreases testosterone levels in men with benign prostatic hyperplasia](/images/research/78f56da0-3ff1-41a6-bcf3-92023f238da5/small/18646.jpg)
research Finasteride, not tamsulosin, increases severity of erectile dysfunction and decreases testosterone levels in men with benign prostatic hyperplasia
Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.
![Testosterone in Women: Measurement and Therapeutic Use](/images/research/831a64e3-2403-4750-b2b1-6a0df9597246/small/13915.jpg)
research Testosterone in Women: Measurement and Therapeutic Use
Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.
![Persistent erectile dysfunction in men exposed to the 5α-reductase inhibitors, finasteride, or dutasteride](/images/research/f7bafa26-1fd1-4d92-ac8a-5c37a06e10d9/small/4000.jpg)
research Persistent erectile dysfunction in men exposed to the 5α-reductase inhibitors, finasteride, or dutasteride
Using finasteride or dutasteride may cause long-lasting erectile dysfunction.
![Adverse Event Reporting in Clinical Trials of Finasteride for Androgenic Alopecia: A Meta-analysis.](/images/research/281de711-5fd2-4db5-b8ce-102b9817970b/small/3613.jpg)
research Adverse Event Reporting in Clinical Trials of Finasteride for Androgenic Alopecia: A Meta-analysis.
Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.
![Effects of Exercise Combined with Finasteride on Hormone and Ovarian Function in Polycystic Ovary Syndrome Rats](/images/research/12d9fcec-afa0-4e3b-a8f8-bdd3defe4f49/small/4497.jpg)
research Effects of Exercise Combined with Finasteride on Hormone and Ovarian Function in Polycystic Ovary Syndrome Rats
Exercise and finasteride together improve ovary health in PCOS rats.
research ODP265 Bph, Androgenic Alopecia, and Acne – Markers of Progesterone Deficiency
![Potential targets in the discovery of new hair growth promoters for androgenic alopecia](/images/research/c04ea5fe-328f-40b5-8f56-0ce38fbf3e69/small/3464.jpg)
research Potential targets in the discovery of new hair growth promoters for androgenic alopecia
The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
![The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer and Depression](/images/research/1d65d7d8-24c2-4cc3-816c-a38bd8d67e17/small/20281.jpg)
research The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer and Depression
5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.
![Comments concerning the real risk of sexual adverse events secondary to the use of 5-ARIs](/images/research/273e930a-50a6-4892-ad73-226287024871/small/18523.jpg)
research Comments concerning the real risk of sexual adverse events secondary to the use of 5-ARIs
The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.
![Long-term dutasteride therapy in men with benign prostatic hyperplasia alters glucose and lipid profiles and increases severity of erectile dysfunction](/images/research/ac0c13c1-a57f-4a2e-b94a-ca835d01570a/small/18221.jpg)
research Long-term dutasteride therapy in men with benign prostatic hyperplasia alters glucose and lipid profiles and increases severity of erectile dysfunction
Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.
![Hair Loss in Women](/images/research/7fcb0851-8367-4a5f-8cfd-8b3aa0a29d4c/small/3566.jpg)
research Hair Loss in Women
Obstetrician/gynecologists can diagnose and manage female hair loss with careful history taking and examination.
research Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It’s Time to Sound the Alarm
![New Nonsteroidal Molecules as Blockers of the Steroidogenic Pathway](/images/research/8cc50190-c0af-4477-854c-0ca968929d6b/small/5552.jpg)
research New Nonsteroidal Molecules as Blockers of the Steroidogenic Pathway
New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.
![Androgenetic alopecia: An autosomal dominant disorder](/images/research/e8dbe281-d12a-4b68-ab8a-fb7c57095328/small/2059.jpg)
research Androgenetic alopecia: An autosomal dominant disorder
Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.
research Androgen action on human skin – from basic research to clinical significance
Hormones like testosterone affect skin functions and can cause skin issues when in excess; treatments to manage these effects are only somewhat effective.
![Finasteride](/images/research/7975a48b-c79f-457e-97c0-a2b68915717e/small/2026.jpg)
research Finasteride
Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
![Expression of steroidogenic enzymes in human sebaceous glands](/images/research/ca574fcf-c40b-4c77-93f5-8910e3339e98/small/31133.jpg)
research Expression of steroidogenic enzymes in human sebaceous glands
Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
![Hair aging and anti-aging](/images/research/8752c3d3-f885-4deb-90c8-a3015160af17/small/20403.jpg)
research Hair aging and anti-aging
Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.
![Haut und Haar](/images/research/f7b801f7-20dd-4048-b573-3726e4fe3829/small/26576.jpg)
research Haut und Haar
The document concludes that protecting skin from the sun, avoiding smoking, and using treatments like Minoxidil and Finasteride can help manage skin and hair aging.
research Rapid nongenomic modulation by neurosteroids of dendritic spines in the hippocampus: Androgen, oestrogen and corticosteroid
Sex and stress steroids quickly change brain cell structures in the hippocampus.
![Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives](/images/research/22ca8539-6e7c-4269-937f-87a4b2b13a2e/small/28160.jpg)
research Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives
Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
![Endocrinological evaluation and hormonal therapy for women with difficult acne](/images/research/7f76de37-ddc6-4917-aeb4-d145322e542a/small/15468.jpg)
research Endocrinological evaluation and hormonal therapy for women with difficult acne
Hormonal therapy is a good option for women with severe acne, especially when there's a chance of hormone imbalance.
![Hormonal Therapy for Acne](/images/research/c8670619-6b1e-456b-b4df-9a787c39a687/small/20532.jpg)
research Hormonal Therapy for Acne
Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.
![Design and synthesis of novel androgen receptor antagonists with sterically bulky icosahedral carboranes](/images/research/b9c9f305-08ab-4148-b712-c2dff022158a/small/33076.jpg)
research Design and synthesis of novel androgen receptor antagonists with sterically bulky icosahedral carboranes
New compounds with carborane showed anti-androgen effects similar to flutamide.
![Androgenetic Alopecia in Women](/images/research/9dd79b54-1ccc-4f44-8fd2-d1c3f4174cf1/small/2475.jpg)
research Androgenetic Alopecia in Women
Androgenetic alopecia in women needs more research and better management strategies.