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In this case series, dual-targeted therapy was observed to provide promising clinical responses in refractory inflammatory bowel disease, with 88.23% to 100% response rates across 9 months and an endoscopic response in 88.89% of evaluated patients, though some adverse events occurred.

Self-management can help improve symptoms of benign prostatic hyperplasia.

This source reports that trastuzumab deruxtecan improves outcomes in HER2-positive and HER2-low metastatic breast cancer, emphasizing the need for careful adverse event monitoring, particularly for interstitial lung disease, and managing emetic risk to maximize benefits.

In this study, a combination of terbinafine and mitotane was used to treat a dog with pituitary-dependent hyperadrenocorticism and dermatophytosis, showing regrowth of hair and negative fungal cultures without detectable adverse effects.

This editorial comment discusses combination therapy for benign prostatic hyperplasia but presents no new research findings.

This study found that NFIB and STAT5 work together to regulate mammary-specific genetic programs in mice, with their combined absence hindering functional alveoli formation.

Eating disorders are serious, often undiagnosed conditions requiring early treatment, with anorexia being the most deadly and binge-eating the most treatable.

This study suggests that behavior modification, semistarvation ketogenic regimens, and surgical therapy could be experimental approaches for different degrees of obesity, with their efficacy varying by the degree of weight excess.

The authors report a dementia patient who developed severe trichotillomania unresponsive to SSRIs, which improved with quetiapine; they suggest dopamine blockade may manage such symptoms in dementia.

This study suggests that combining bendamustine with tucidinostat may improve survival in patients with relapsed or refractory adult T-cell leukemia/lymphoma, highlighting its potential for clinical investigation.

This study reports on biofeedback treatment for dysfunctional voiding in three adult cases, providing insights into this condition when diagnosed beyond childhood.

This case report describes significant improvements in both trichotillomania and bulimia symptoms with N-acetylcysteine treatment, suggesting a potential shared pathophysiological mechanism between the disorders.

This narrative review presents composite cases of individuals undergoing gender-affirming care, illustrating varied outcomes without reporting new clinical results or systematic findings.

This article discusses the relationship between sedentary behavior and chronic disease, proposing that "physical inactivity disease" may be a non-permissive brain disorder with various physiological effects, but it reports no new research results.

This study observed that gender-affirming hormone therapy differentially affects metabolism in mice, with the specific metabolic impacts dependent on the type of hormonal treatment used.

This report describes an 8-year-old male with trichotillomania, confirmed by trichoscopy showing characteristic hair damage and patterns.

In this case report, a patient with a history of discoid lupus erythematosus experienced an exacerbation of the condition after topical immunotherapy for alopecia areata, suggesting contact dermatitis as a potential trigger.

In this study, higher DHA/omega-6 fatty acid ratios were linked to increased social impairment in individuals with autism, alongside lower antioxidant enzyme levels and higher markers of lipid peroxidation.

In a DNFB-induced mouse model of atopic dermatitis, this study found that both topical and oral formulations of the probiotic Bifidobacterium animalis J12 improved AD symptoms through distinct mechanisms, with topical applications reducing local inflammation and oral administration enhancing gut microbiota and reducing systemic inflammation.

This study of monozygotic transgender male twins observed that consistent hormone therapy led to physical changes such as deepening voice and increased facial/body hair, with no reported mood-related adverse effects.

This study found that dermatology patients with tattoos or piercings may have a higher risk of body dysmorphic disorder tendencies and lower acceptance of their illness.

In this study, body dysmorphic disorder symptoms in dermatological patients were strongly linked to psychiatric issues and reduced quality of life, particularly among those with unclassified dermatoses.

The author improved his health by adopting mindfulness and a healthier lifestyle.

This study reported that seed germination and root hair growth were significantly enhanced after exposure to an individual whose depression was treated with Emotional Freedom Techniques, suggesting that human mood may influence seed viability.

This study found that neurosteroids and benzodiazepines decrease network excitability in neuronal cultures, with specific long-term depressive effects on inhibitory neurons.

This article presents guidelines developed by a multidisciplinary expert panel for the care of adolescent transgender and non-binary individuals with gender dysphoria, emphasizing individualized, affirmative care to enhance well-being and quality of life.

DNCB is highly effective for treating alopecia areata with minimal long-term side effects.

In this case report, a 70-year-old woman with a history of autoimmune hypothyroidism experienced alternating hypothyroidism and hyperthyroidism over a decade, highlighting the potential role of thyrotropin receptor autoantibodies in these fluctuations.

This review discusses the classification and treatment of ejaculatory dysfunction, outlining both pharmacotherapy and behavioral therapy as primary interventions, but does not present new clinical findings.

This study found that the decision board is a reliable and valid tool for assessing treatment preferences in systemic lupus erythematosus patients, who tended to favor oral medication due to concerns about side effects.