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Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Anabolic steroid users may face higher risk of severe COVID-19.

A woman with severe angioedema improved significantly after treatment with rituximab.

Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Researchers identified five new potential targets for leishmaniasis treatment, suggesting repurposing existing drugs could be effective.

Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.

Medications for glucose metabolism and weight control, combined therapy options, and herbal medicines may help regulate menstrual cycle in adolescents with PCOS.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

Combining DHT and EDC improves the strength and stability of PADM scaffolds for tissue engineering.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.

Overweight women with PCOS have higher levels of certain hormones that could indicate a higher risk of heart and metabolic problems.

After prostate removal surgery, higher initial prostate size was linked to higher urethral PSA levels and more severe male pattern baldness.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Lower SHBG levels may increase the risk of PCOS.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.

PCOS has a strong genetic basis, but more research is needed to fully understand it.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

The paper suggests that France's suspension of Diane-35 was hasty and could cause treatment issues and unintended pregnancies, recommending a re-evaluation and better patient information.

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Statins may help treat PCOS by lowering androgen levels and improving cholesterol.