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Yifa compound effectively treats female pattern hair loss and lowers DHT and DHEA levels.

Combining DHT and EDC improves the strength and stability of PADM scaffolds for tissue engineering.

Cinnamaldehyde helps bone healing initially but may slow healing later unless combined with DHT treatment.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Androgens can both increase and decrease hair growth in different parts of the body.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Too much androgen can cause hair loss; finasteride may help.

Finasteride effectively blocks enzyme causing male pattern baldness.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Higher androgen levels and site-specific AR expression cause sex-related skeletal differences, and certain steroids can boost AR expression and androgen effects in bone cells.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.

Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Hormones like testosterone and estrogen significantly affect hair growth and structure.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.