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A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

New treatments for male hypogonadism are effective and should be personalized.

Sex hormones, especially androgens, play a key role in causing acne.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

18β-glycyrrhetinic acid from licorice root is good for skin and hair treatments but has absorption challenges.

New genes and pathways are important for testosterone production and male sexual development.

Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Finasteride effectively reduces hair loss by decreasing androgen levels.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Cuscuta reflexa extract may help treat hair loss caused by hormones.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

Anabolic steroids may help prevent aging effects by reducing toxicity, not by their usual functions.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Genetics and hormones cause hair loss; finasteride treats it safely.

Prostate cells have proteins that bind to specific hormones, which can increase protein production when activated by these hormones.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Finasteride helps reduce heart issues and improves heart function.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.