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The document concludes that current treatments for androgenic alopecia are not fully effective, but new therapies like botulinum toxin and PRP show promise, and future gene therapy could be beneficial.

Finasteride does not negatively affect male reproductive function.

Androgens can both increase and decrease hair growth in different parts of the body.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Finasteride effectively blocks enzyme causing male pattern baldness.

Male pattern baldness involves hormones and cell signals affecting hair growth.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

Genetics and hormones cause hair loss; finasteride treats it safely.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Genes and hormones cause hair loss, with four genes contributing equally.

Red Ginseng Extract may help human hair grow by activating growth pathways and blocking negative effects of certain hormones.

Androgens prevent hair growth by changing Wnt signals in cells.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Finasteride effectively reduces hair growth in women with polycystic ovary syndrome or idiopathic hirsutism.

Apigenin may help promote hair growth and could treat hair loss.

Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

New compounds may soon be tested to treat excessive hair growth in women.

There is no significant link between male pattern baldness and insulin resistance.