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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Fungi-produced compounds can change plant root growth.

Hair stem cell regeneration is controlled by signals that can explain different hair growth patterns and baldness.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.