January 2025 in “Brazilian Journal of Veterinary Medicine/Revista Brasileira de Medicina Veterinária” This source describes the first successful use of a deslorelin acetate implant to treat alopecia X in a neutered female dog, achieving profuse hair regrowth in 9 months, suggesting an uncomplicated and cost-effective alternative after melatonin failure.
3 citations
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May 2018 in “The Journal of the American Animal Hospital Association/Journal of the American Animal Hospital Association” In this study, a single deslorelin acetate implant led to substantial and sustained hair regrowth in two sexually intact male keeshonden with hair cycle arrest.
October 2023 in “Russian Journal of Veterinary Pathology” This source reviews existing studies on treating canine noninflammatory alopecia, identifying microneedling and oral administration of certain drugs as optimal methods with fewer side effects, while noting that other treatments like mitotane and minoxidil cause serious side effects, limiting their future use.
January 2015 in “VetPharma” This review discusses Alopecia X in plush-coated dogs, noting that while treatments like melatonin and laser therapy have shown promise, the condition is generally considered a cosmetic issue without the need for therapy.
6 citations
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February 2009 in “Veterinární Medicína” This study found that deslorelin implants can effectively reduce estradiol levels and support hair regrowth in neutered ferrets with hyperoestrogenism caused by nodular hyperplasia of the adrenocortex.
March 2026 in “Brazilian Journal of Animal and Environmental Research” This study observed that deslorelin acetate implants reduced sexual activity and improved coat quality in a German Spitz dog with alopecia X, suggesting its potential as a less invasive and reversible treatment for managing reproductive function and this dermatopathy.
6 citations
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January 2013 This chapter reviews hyperadrenocorticism in ferrets, covering its causes, symptoms, diagnosis, and treatment options, but reports no new research findings.
10 citations
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July 2014 in “Veterinary dermatology” This study found that deslorelin may promote hair regrowth in intact male dogs with hair cycle arrest, but had no effect on neutered females.
Different drugs are used to manage breeding, prevent or end pregnancy, and treat reproductive issues in dogs and cats.
1 citations
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August 2022 in “Veterinary medicine and science” This review discusses various diagnostic and treatment strategies for canine prostate diseases, including pharmacological options and advanced procedures, but reports no new clinical results.
19 citations
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January 2008 in “The veterinary clinics of North America. Exotic animal practice” This review discusses adrenal gland disease in ferrets, exploring its signs, potential contributing factors, and current treatment options, but it reports no new clinical results.
September 2016 in “Elsevier eBooks” Different types of hair loss in dogs and cats have various causes and treatments, with outcomes ranging from good to uncertain.
17 citations
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January 2015 in “MedChemComm” New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
1 citations
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December 2017 in “Research for Rural Development/Research for Rural Development (Online)” This study found no correlation between clinical signs and sex steroid levels in ferrets with hyperadrenocorticism and noted that androstenedione was elevated in many cases.
5 citations
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May 2021 in “Veterinary medicine and science” In this study, cosyntropin-induced cortisol spikes did not affect hair cortisol concentration in captive grizzly bears, contrasting with stress responses observed in free-ranging bears during capture.
February 1999 in “Drugs in R & D” The document concludes that various drugs for men's health issues are in development, with treatments for sexual dysfunction and prostate conditions being the most advanced.
September 2008 in “UK vet. Companion animal” This article updates on the medical management of benign prostatic hyperplasia in companion animals and reports no new clinical findings; the authors discuss existing treatments.
4 citations
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January 2001 in “PubMed” This study found that delmadinone acetate and finasteride caused a reversible suppression of prostate gland activity in male dogs, with delmadinone acetate also temporarily altering epididymal sperm maturation.
12 citations
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July 2015 in “Veterinary Dermatology” This study observed that microneedling induced significant hair regrowth and reduced hyperpigmentation in two Pomeranians with alopecia X, with stable results over 12 months.
4 citations
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July 2015 in “Veterinary Dermatology” This study identified the expression of 5αR1 and 5αR3 enzymes in canine skin, which may advance understanding and treatment of alopecia X.
March 2023 in “Enciclopédia Biosfera” The researchers reported that finasteride was effective in controlling hormone-related dysfunction in an adult dog diagnosed with benign prostatic hyperplasia, although the condition regressed after the medication was withdrawn.
17 citations
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October 2006 in “Molecular and Cellular Endocrinology” This study found that the L457(3.43)R mutation in the human luteinizing hormone receptor increases phosphodiesterase activity, reducing hormonal response despite elevated basal cAMP levels.
6 citations
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August 2020 in “JCRPE” This report presents a case of familial male-limited precocious puberty with a novel LHCGR gene mutation, where a boy responded well to treatment with bicalutamide and anastrozole.
2 citations
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December 2019 in “Veterinary Dermatology” This study found that in dogs with post-clipping alopecia, microneedling with platelet-rich plasma may induce more rapid hair regrowth compared to microneedling alone, though results were similar by six months.
May 2025 in “American Journal of Veterinary Research” Photobiomodulation did not significantly improve hair density in dogs with alopecia X.
July 2022 in “Research, Society and Development” This study observed variable therapeutic responses in dogs with Alopecia X, with some showing complete hair regrowth while others did not, following similar treatments including orchiectomy and supplementation.
September 2015 in “Advances in small animal medicine and surgery” Deslorelin can help regrow hair in most intact male dogs with alopecia.
February 2026 in “Revista Saber Digital” In this case report, researchers described a German Spitz dog with alopecia X, emphasizing successful hair regrowth with deslorelin treatment, highlighting its efficacy as a therapeutic option and the necessity for accurate diagnosis in veterinary dermatology.
September 2015 in “Veterinary Dermatology” This study found that microneedling induced nearly complete hair regrowth in two Pomeranians with alopecia X, suggesting it may be a promising alternative treatment for similar hair cycle arrest disorders.
14 citations
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April 2005 in “African Journal of Reproductive Health” This article reviews non-biodegradable progestational subdermal implants as long-acting contraceptives for women, discussing their effectiveness, associated side effects, and implementation challenges without reporting new clinical results.