35 citations
,
February 1993 in “International Journal of Dermatology” This report describes two cases where pemphigus lesions developed at sites of cosmetic procedures, suggesting these treatments might trigger the disease and should be distinguished from other post-surgery complications.
46 citations
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January 2020 in “Research” This review discusses the design, properties, and potential applications of smart microneedles, with no new clinical results presented.
June 2007 in “CRC Press eBooks” Aesthetic mesotherapy can improve the appearance of the face and hair.
This pilot study employed in-vivo multiphoton microscopy to visualize pigment-producing melanocytes in vitiligo patients, aiming to enhance understanding of treatment impacts and potentially improve transplantation therapies.
1 citations
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November 2024 in “Revista Foco” This review suggests that PRP is an effective and safe technique for skin rejuvenation in aesthetic procedures, based on existing literature.
1 citations
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February 2021 This study observed that using ice pack compression or a vibration anesthesia device reduced pain during inactivated PRP scalp injections in patients with alopecia, suggesting both as inexpensive and accessible pain-relief options.
April 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, Platycladus orientalis leaf extract loaded into hyaluronic acid microneedles was found to promote hair follicle growth by enhancing the environment for hair cell proliferation and activating repair pathways, suggesting potential as a treatment for androgenic alopecia.
August 1994 in “Journal of Dermatological Science”
January 2024 in “International Journal of Scientific Research in Science and Technology” This review analyzes Platelet-Rich Plasma therapy for facial aesthetics, discussing its principles, efficacy, safety, and future research directions, but reports no new clinical results.
July 2025 in “Nano Research” This review highlights the application of microneedle technology as a promising advancement in psoriasis management, focusing on its roles in enhanced transdermal drug delivery and minimally invasive biomarker monitoring, while also discussing current challenges and future research directions.
September 2025 in “Intisari Sains Medis” This case report from this study demonstrates the potential of treating severe alopecia areata with a combination of microneedling, minoxidil, desoximetasone, and methylprednisolone, noting initial hair regrowth after 14 days but emphasizing the need for further research to confirm long-term efficacy and safety.
92 citations
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June 2017 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This review found that microneedling appears to be a safe and effective option for treating scars and wrinkles, with fewer side effects and shorter recovery time than some other treatments.
July 2025 in “Journal of Investigative Dermatology” In this study, AMP-303 injections demonstrated a trend toward increasing non-vellus hair count in men with mild to moderate androgenetic alopecia, notably showing a 14.5% peak increase at 60 days compared to saline, with effects lasting up to five months.
In this study on mice, a baricitinib-loaded microneedle patch enhanced hair growth in alopecia areata lesions (68% vs control: 33%, p < 0.05), suggesting it may deliver treatment effectively and pain-free, with fewer systemic side effects.
August 2026 in “Cell Biomaterials” D-chiral biomaterial scaffolds enhance tissue and hair regeneration by activating the body's immune system.
1 citations
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April 2026 in “Aesthetic Plastic Surgery” This study found that radiofrequency microneedling is effective and well-tolerated for improving various skin conditions, showing comparable efficacy to fractional lasers for atrophic acne scars with generally favorable patient satisfaction and safety.
6 citations
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August 2013 in “Facial plastic surgery clinics of North America” This article discusses the philosophy and strategies for dense packing in hair transplantation, emphasizing that not all patients are candidates, and reports no clinical results.
5 citations
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November 2015 in “Journal of Cosmetic Dermatology” This review discusses pain management strategies for optical permanent hair removal, which causes pain due to the increase in skin surface temperature, but reports no new experimental results.
2 citations
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May 2022 in “Advanced therapeutics” This study reported that a novel vasodilator drug called TOP-M119, when delivered using a specially designed dissolving microneedle system, showed enhanced targeting of hair follicles and effectiveness in treating alopecia, demonstrated through in vitro, ex vivo, and in vivo studies involving mouse skin.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reported that adipose stem cell exosomes, combined with microneedling, improved facial skin wrinkles, elasticity, hydration, and pigmentation compared to a placebo, with significant results on the Global Aesthetic Improvement Scale and no serious adverse events noted in treated individuals.
July 2018 in “Plastic and Aesthetic Nursing” This research abstract provides information about the publisher, Wolters Kluwer Health, and the journal's subscription services, but it doesn’t describe a specific study or research findings. Results are not reported.
87 citations
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March 2017 in “Journal of Clinical Investigation” In this study, researchers identified PSENEN mutations that can lead to a form of Dowling-Degos disease, characterized by follicular hyperkeratosis and an increased susceptibility to acne inversa, especially in the presence of certain trigger factors.
January 2020 in “Hair transplant forum international” This review discusses exosomal micro RNAs from dermal papilla cells in hair follicle mediation and reports no new clinical results.
June 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study tested a microneedle patch on rabbit and pig models to support skin regeneration, revealing that the treatment accelerated wound closure, reduced scar formation, and promoted hair-bearing tissue and follicle growth, suggesting a trauma-guided framework for skin restoration.
January 2026 in “International Society of Hair Restoration Surgery” This study reports that a novel multimodal approach, combining tattoo machine–assisted drug delivery of hair loss treatments with oral and topical medications, may enhance hair density and thickness in androgenetic alopecia patients, though larger controlled studies are needed to confirm these early findings.
2 citations
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December 2019 in “Electronic Journal of General Medicine” This study found that combining microfocused ultrasound with autologous blood cell factors significantly improved skin rejuvenation compared to using microfocused ultrasound alone.
November 2021 in “Arquivos Médicos dos Hospitais e da Faculdade de Ciências Médicas da Santa Casa de São Paulo” This review of current research suggests that combining microneedling with minoxidil, and possibly platelet-rich plasma or mesotherapy, may achieve better hair growth results for androgenetic alopecia than conventional methods.
5 citations
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January 2016 in “Surgical and Cosmetic Dermatology” 2 citations
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September 2023 in “JAAD Case Reports” This article discusses the chronic inflammatory skin diseases acne keloidalis nuchae and dissecting cellulitis of the scalp, focusing on their shared etiology and differing progression, and reports no new clinical findings.
April 2016 in “Journal of Investigative Dermatology” This study found that administering botulinum toxin A via Flex-PADs to mouse footpads inhibited sweating similarly to traditional injections, suggesting a promising patient-friendly delivery method for hyperhidrosis treatment.