July 2025 in “Phytomedicine Plus” This study reported that Cyperus rotundus L., a plant used in traditional medicine, effectively reduces hair growth with minimal side effects, showing efficacy comparable to Alexandrite laser treatments in certain cases, particularly for white hair, positioning it as a potential natural alternative to chemical depilatories.
26 citations
,
July 2012 in “Journal of family planning and reproductive health care” This review explores treatment approaches for excess male-pattern body hair in women and emphasizes the importance of effective management, but reports no new clinical findings.
5 citations
,
February 2022 in “Animals” This study found that electric shaving was the most effective and safest method for preoperative hair removal in mice, compared to depilatory cream and sodium sulfide, which negatively affected wound healing.
August 2026 in “International Journal of Molecular Sciences” This study found that Atractylodes macrocephala Koidz. extract promotes anagen entry and hair regrowth by enhancing dermal papilla cell activity and supporting hair cycle progression in a mouse model.
September 2024 in “Journal of Microbiology and Biotechnology” In this study, the researchers found that their conductive bio-harvesting tonic enhanced hair follicle proliferation and delayed regression with electric stimulation and the antifungal agent 6-pentyl-α-pyrone in both mice and human hair follicle tests.
12 citations
,
January 2007 in “Current problems in dermatology” This review discusses the impact of various exogenous agents on hair, such as cosmetics and radiation, but reports no new experimental results.
1 citations
,
January 2013 This review examines the design and evaluation parameters of depilatory formulations but reports no new empirical findings.
55 citations
,
January 2002 in “Journal of liposome research” This research explores developing liposomal formulations to enhance the delivery of difficult-to-absorb agents directly to hair follicles and sebaceous glands, with minoxidil and plasmid DNA as study molecules.
64 citations
,
January 2015 in “BioMed Research International” In this study, topical application of fibroblast growth factors was found to promote hair growth by inducing and prolonging the anagen phase in telogenic C57BL/6 mice, suggesting potential as hair growth-promoting agents.
December 2024 in “Globus: an international journal of medical science, engineering and technology.” This study found that 10% Citrus aurantium peel oil significantly promoted hair growth in ICR mice by reducing the time needed for hair growth initiation and completion, and by increasing hair length, follicle diameter, and count, showing potential as a hair growth agent.
3 citations
,
May 2024 in “Cureus” This review revisits hair-thread tourniquet syndrome, highlighting the importance of prompt diagnosis and treatment by removing the constricting hair or similar substance to prevent damage to affected body parts, aiming to raise healthcare professionals' awareness for better prevention and management.
November 2021 in “Journal of pharmaceutical research international” This review examines the benefits and preparation methods of herbal versus chemical depilatories, highlighting the potential safety and efficacy advantages of herbal ingredients but provides no new experimental findings.
September 2018 in “Gynecology & Obstetrics” In a meta-analysis of 210 hair tourniquet syndrome cases, this study reported that 44.2% involved the penis, 40.4% the toes, and 8.6% fingers, highlighting the condition's potential severity and underreporting, especially in infants and some adults with cognitive impairments.
12 citations
,
December 2023 in “Journal of Applied Pharmaceutical Sciences and Research” In this research, caffeine's versatile pharmacological actions were highlighted, demonstrating its stimulant, bronchodilator, diuretic, and potential anticancer effects through interactions with adenosine receptors, phosphodiesterase, and renal tubules, revealing valuable insights for drug development and therapeutic applications in medicine.
33 citations
,
September 2012 in “Wound Repair and Regeneration” This study found that the application of calreticulin significantly improved wound healing time and quality in diabetic mice, suggesting it may be an effective topical treatment for chronic wounds.
18 citations
,
January 2003 in “Gynecological Endocrinology” In this study, low-dose finasteride (2.5 mg/day) significantly reduced hirsutism scores in women over 12 months without significant hormonal changes or serious side effects.
17 citations
,
January 2019 in “Journal of cancer” This study found that the medicinal formula YH0618 may reduce toxicity from the chemotherapy drug doxorubicin, improving side effects like hair loss and organ damage, while maintaining its anti-cancer effects.
12 citations
,
May 2014 in “International Journal of Molecular Medicine” This study suggests that the water fraction of Chrysanthemum zawadskii extract promotes hair growth by inducing telogen hair follicles in mice to enter the anagen phase and stimulating cell differentiation.
August 2024 in “Life Science Alliance” This study found that topical application of TGF-β mimic promoted enhanced wound healing and tissue regeneration in mice, suggesting its potential as a therapeutic option for improving wound healing.
March 2026 in “Trends in Sciences” This study developed a testosterone propionate-induced C57BL/6 mouse model of androgenetic alopecia, demonstrating that high-dose, prolonged testosterone administration inhibited hair regrowth and mirrored human AGA pathology, providing a useful platform for studying hair loss mechanisms and testing therapies targeting the Wnt/β-catenin pathway.
June 2022 in “International journal of drug delivery technology” This study found that Convolvulus arvensis ethanolic extract may promote hair growth and reduce hair loss in albino mice with testosterone-induced baldness by increasing follicular density and the anagen/telogen ratio.
43 citations
,
May 1978 in “JAMA” Minoxidil controls blood pressure but may cause kidney damage and needs diuretics to prevent swelling.
2 citations
,
September 1980 in “Experientia” Polyethylene alanine caused hair loss in young lab animals but not in adults, with hair regrowth occurring within 20 days.
9 citations
,
August 2005 in “Experimental Dermatology” In this study, the researchers report that a modified epimorphin-derived peptide shows potential for hair follicle regeneration, especially when used with 1% minoxidil in mice.
July 2002 in “Journal of Cosmetic Dermatology” This article reviews the effectiveness of laser technology and Eflornithine cream as modern methods for reducing unwanted hair growth and reports no new clinical results.
10 citations
,
June 2019 in “International Journal of Pharmaceutics” Hair removal methods damage the skin barrier and affect substance penetration.
May 2024 in “Cell proliferation” This study found that melatonin supplementation significantly promoted hair regeneration in a hair depilation mouse model by up-regulating the Wnt/β-catenin signaling pathway in dermal papillae and hair follicle stem cells, suggesting potential implications for human hair loss treatments.
55 citations
,
October 2008 in “American Journal Of Pathology” mIGF-1 in skin cells speeds up wound healing and hair growth in mice without harmful effects.
26 citations
,
August 2008 in “Clinical endocrinology” This paper summarizes proceedings from a PCOS Special Interest Group, reporting recent advances in the understanding of PCOS follicular abnormalities, associated cardiovascular risks, and dermatological issues, but does not present new clinical findings.
May 2026 in “Cell Reports Medicine” This study develops FR-1, a topical small molecule, which reduces scarring and avoids skin atrophy in a murine wound model, showing potential for treating fibrosis without the side effects of current therapies.