Search
for
Sort by
Research
390-420 / 1000+ results
research Pomegranate-peel-chitosan-gelatin composite: A hemostatic dental sponge with antibacterial enhancement
This study developed a biodegradable gelatin and chitosan hemostatic sponge, enhanced with pomegranate peel extract, for dental applications, highlighting its effective antibacterial properties, improved blood absorption, and reduced clotting time, suggesting potential for use in clinical dental and wound care procedures.
research Elucidation of the Underlying Mechanism of Gujian Oral Liquid Acting on Osteoarthritis through Network Pharmacology, Molecular Docking, and Experiment
This study suggests that Gujian oral liquid may reduce osteoarthritis symptoms by regulating inflammation and catabolism through the TNF-α/NF-kappa B signaling pathway, as confirmed by both in vivo and in vitro experiments.
research Efficacy and Acceptability of a New Water-Soluble Nail Strengthener Containing Pistacia lentiscus and Hyaluronic Acid to Improve the Appearance of Brittle Nails versus Untreated Nails: In vitro and Clinical Evidence
In this study, a water-soluble nail strengthener containing Pistacia lentiscus and hyaluronic acid significantly improved the appearance and firmness of brittle nails in both in vitro and clinical settings.
research Role of the Chinese Herbal Medicine Xianhuayin on the Reversal of Premalignant Mucosal Lesions in the Golden Hamster Buccal Pouch
This study concluded that the Chinese herbal medicine Xianhuayin effectively reversed DMBA-induced premalignant lesions in the buccal pouch of golden hamsters.
research Three months extended-release microspheres prepared by multi-microchannel microfluidics in beagle dog models
This study demonstrated that finasteride-loaded PLGA microspheres created using a novel microfluidic device exhibit extended drug release in beagle dogs, with modifications allowing for release up to 3 months.
research Comparison of Calcium and Barium Microcapsules as Scaffolds in the Development of Artificial Dermal Papillae
This study found that calcium microcapsules exhibited better biocompatibility and cell viability than barium microcapsules for scaffolding in artificial dermal papilla, suggesting potential for developing new hair follicle structures.
research Development and Characterization of Dutasteride Bearing Liposomal Systems for Topical Use
This study found that a dutasteride-loaded liposomal system significantly increased skin permeability and drug deposition in mouse skin compared to other formulations, suggesting improved localized treatment potential for androgenetic alopecia.
research Prevention by vitamin D2in combination with milk protein of hair loss caused by drugs.
research Fabrication of polyvinyl pyrrolidone-K90/Eudragit RL100-based dissolving microneedle patches loaded with alpha-arbutin and resveratrol for skin depigmentation
This study investigated the use of dissolving microneedle patches to improve the skin-lightening effects of alpha-arbutin and resveratrol, finding that the patches enhanced intradermal delivery and slightly decreased the melanin index without affecting skin hydration or causing irritation over 24 hours.
research A Case of Alopecia due to Oral Contraceptives
research Culture of human dental pulp cells at variable times post-tooth extraction
In this study, it was found that dental pulp cells from extracted teeth can be preserved at room temperature for up to five hours without affecting their viability or proliferative potential.
research Virtual Bioequivalence Assessment of Ritlecitinib Capsules with Incorporation of Observed Clinical Variability Using a Physiologically Based Pharmacokinetic Model
This study demonstrates that bioequivalence for proposed 50-mg ritlecitinib capsules versus clinical 100-mg capsules can be supported using a PBPK model-based biowaiver, achieving over 90% probability of success.
research Formulation and design of finasteride coated microneedles
This study found that coated microneedles promoted drug release effectively, comparable to marketed minoxidil solutions, with stable performance over 30 days at high temperatures.
research A smart polyhydroxyalkanoate-hyaluronic acid hybrid biphasic delivery platform for enhanced Alzheimer’s symptom management via sustained huperzine A release
In this study, researchers developed a novel delivery system using hyaluronic acid gels to encapsulate Huperzine A for Alzheimer's treatment, achieving extended release over 20 days and significantly improving pathology and behavior in mice, including enhanced memory and reduced neuroinflammation.
research Socket Preservation Following Extraction A Review Article
This article reviews various aspects of dental socket healing after tooth extraction, including grafting techniques and their role in dental implant placement, and reports no new clinical results.
research Tooth Regeneration: Insights from Tooth Development and Spatial-Temporal Control of Bioactive Drug Release
This review discusses the progress in tooth regeneration research and highlights the potential of spatial-temporal release of developmental factors, but it reports no new clinical findings.
research Comparison of the therapeutic effects of the dietary and topical forms of Zizyphus jujuba extract on oral mucositis induced by 5-fluorouracil: A golden hamster model
This animal study found that both systemic and topical forms of Zizyphus jujuba extract were associated with reduced severity of oral mucositis in golden hamsters treated with 5-fluorouracil.
research Dynamet wins titanium award
This study found that dihydrotestosterone induces hair loss in male C57BL/6 mice, and this effect can be partially reversed by the androgen receptor antagonist bicalutamide.
research Physicochemical characterization of finasteride:PEG 6000 and finasteride:Kollidon K25 solid dispersions, and finasteride: β-cyclodextrin inclusion complexes
This study found that forming solid dispersions and inclusion complexes of finasteride significantly increased its solubility compared to its pure form.
research Formulation and Evaluation of Herbal Gummies
The study developed herbal hair gummies using ingredients like fenugreek, amla, and bhringraj, alongside folic acid, zinc, and biotin, concluding they are palatable, meet quality standards, exhibit antioxidant properties, and may effectively enhance hair growth and reduce hair loss.
research Dovobet ointment under occlusion overnight for troublesome scalp psoriasis
Dovobet ointment used overnight effectively reduces scalp psoriasis severity and itch.
research Dental manifestations in Vitamin D dependent rickets Type II with Alopecia: a short pictorial case report
This case report presents the dental challenges faced by a child with vitamin D-dependent rickets type II, including early onset rickets, alopecia, and specific dental abnormalities, emphasizing the need for comprehensive, multidisciplinary management.
research Drug Targeting to the Hair Follicles: A Cyclodextrin-Based Drug Delivery
research Determination of the efficacy of terbinafine hydrochloride nail solution in the topical treatment of dermatophytosis in a guinea pig model
This study found that terbinafine HCl nail solutions with or without DDAIP HCl significantly outperformed ciclopirox nail lacquer in treating guinea pig dermatophytosis, suggesting potential effectiveness for human nail infections.
research Selective Delivery of Tofacitinib Citrate to Hair Follicles Using Lipid-Coated Calcium Carbonate Nanocarrier Controls Chemotherapy-Induced Alopecia Areata
In this study, researchers observed that phospholipid-calcium carbonate hybrid nanoparticles effectively delivered Tofacitinib citrate topically, which significantly inhibited hair follicle apoptosis and promoted hair growth in a mouse model of chemotherapy-induced alopecia, compared to a traditional Tofacitinib solution.
research Lipid-based nanoparticles for topical delivery of hair growth therapeutic molecules
This study developed and tested nanostructured lipid carriers for topical dutasteride delivery, finding them stable, low in cytotoxicity and non-irritating, with no drug permeation through pig ear skin over 48 hours.
research Compatibility Studies of Minoxidil with Different Excipients by Using DSC, TGA and FTIR
In this study, researchers found that minoxidil is compatible with excipients such as Beta-cyclodextrin and cellulose, while it is incompatible with Eudragit S 100 and mannitol, indicating potential formulation challenges in pharmaceutical applications.
research Strontium zinc silicate simultaneously alleviates osteoporosis and sarcopenia in tail-suspended rats via Piezo1-mediated Ca2+ signaling
This study suggests that bioactive ceramics could be an effective universal strategy for treating musculoskeletal disorders by targeting the Piezo1-modulated intracellular calcium pathway during bone and muscle formation.
research Distinct tooth regeneration systems deploy a conserved battery of genes
This study found that zebrafish and stickleback fish use similar genetic programs for tooth regeneration, despite differences in their dental structures.