75 citations
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August 2018 in “Plant physiology” In this study, researchers found that increased hydrogen sulfide levels in Arabidopsis disrupted actin dynamics through S-sulfhydration, leading to the depolymerization of actin filaments and inhibited root hair growth.
March 2025 in “International Journal For Multidisciplinary Research” This study reported that silver nanoparticles biosynthesized from the Dracaena trifasciata plant showed strong antioxidant properties but no anti-inflammatory action in vitro, suggesting these findings may warrant further in vivo animal studies.
3 citations
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June 1987 in “British Journal of Dermatology” In this study, nifedipine provided rapid symptomatic relief in most patients with severe recalcitrant perniosis, but some experienced side effects that limited dosage and two patients were lost to follow-up.
January 2004 in “Zhōnghuá yàoxué zázhì” This study successfully synthesized finasteride using a method that avoids expensive reagents and column chromatography, achieving a higher yield than previously reported.
June 2025 in “Samarra Journal of Pure and Applied Science” This study developed a rapid and accurate spectrophotometric method using diazotized sulfanilic acid to measure minoxidil in both pharmaceutical formulations and pure form, demonstrating high precision and linearity within a concentration range of 5-40 μg/ml.
This review explores the synthesis and potential of azasteroids as novel drugs, discussing challenges in their production and reporting no new clinical results.
35 citations
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October 2004 in “Biology of Reproduction” This study found that dual 5α-reductase inhibition in rats led to decreased sperm motility and altered morphology, resulting in subfertility.
This research presentation explored the roles of mammalian multi-copper ferroxidases in iron homeostasis and highlighted new insights into their functions, including non-iron-related ones, while discussing arsenic's role in microbial warfare as a potential antibiotic.
28 citations
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May 2023 in “Current Opinion in Colloid & Interface Science”
This study reported that dandelion herb-derived carbon dots significantly enhanced wound healing in mice with Staphylococcus aureus infections, outperforming a commercial wound healing spray through their antibacterial and dual ROS-modulating capabilities.
3 citations
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April 2015 in “Current problems in dermatology” This study focuses on improving the detection and characterization of an enzyme in guinea pig hair follicles that converts arginine to citrulline, highlighting challenges with assay sensitivity and reproducibility.
January 2006 in “Dianzi xianwei xuebao” This study observed that ultrastructural changes like lamellar bodies and electron-dense granules in the stratum corneum may aid in the early diagnosis of Netherton syndrome.
136 citations
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March 1996 in “Journal of the American Chemical Society” This study explains finasteride's high potency and specificity as a mechanism-based inhibitor for treating benign prostatic hyperplasia by detailing its interaction with human type 2 steroid 5α-reductase.
research News
February 2023 in “Chemistry & Industry” 30 citations
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November 2013 in “SLEEP” This study suggests that inhibiting testosterone via the 5α-reductase pathway might help alleviate sleep-related breathing instability in certain central sleep apnea populations.
February 2025 in “Journal of Forensic Sciences” The study found that sonication washing of hair roots with fewer than 50 visible nuclei could reduce the number of nuclei available for DNA extraction and STR typing, suggesting that for laboratories focused on nuDNA analysis, a gentler washing method might be adequate.
February 2010 in “Journal of The American Academy of Dermatology” NB-002 is a promising new topical treatment for fungal nail infections, showing better results than a non-medicated option.
1 citations
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May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers identified a temperature-sensitive mutation in the FERONIA gene of plants that prevents root hair formation at elevated temperatures, highlighting its role in maintaining root hair growth and response to plant hormones.
18 citations
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January 2018 in “Soil biology”
1 citations
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May 2026 in “Environmental Health Engineering and Management” This study found that white poplar wood sawdust effectively removed up to 92.12% of thallium ions from contaminated water in laboratory conditions, demonstrating its potential as a low-cost adsorbent for reducing toxic thallium levels.
1 citations
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July 2026 in “Asian Journal of Agriculture” In this study conducted under controlled laboratory conditions, warm water and shallot extract were found to significantly speed up the germination of lettuce and napa cabbage seeds compared to untreated seeds, though further testing is needed in nursery or field settings.
64 citations
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October 2018 in “Thérapie” This report describes the enhancement of the French SNIIRAM/SNDS healthcare database through external data linkages, highlighting its potential use in medical research despite complexities in the integration process.
January 2019 in “Le dépôt institutionnel (Université du Québec à Trois-Rivières)” This document is a thesis or dissertation backed by the Université du Québec à Trois-Rivières, and it provides no new research findings.
13 citations
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October 2005 in “Analytical Sciences” This study developed a method using LC/APCI-MS to measure the activity of steroid 5α-reductase, applied to kinetic studies and inhibitory tests with Finasteride in a rat prostatic enzyme model.
January 2006 in “Analytical chemistry, an Indian journal” This study developed two sensitive spectrophotometric methods to accurately determine finasteride in pure and tablet forms, demonstrating linear response and compliance with ICH guidelines.
2 citations
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September 2018 in “Journal of Separation Science” This study demonstrated that using finasteride impurity as a non-isotopically labeled internal standard in paper spray ionization–mass spectrometry can effectively and efficiently measure finasteride tablet dissolution, achieving results comparable to high-performance liquid chromatography.
8 citations
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March 2012 in “Mass spectrometry letters” This study observed that the isotope-dilution GC-MS technique can assess 5α-reductase activity more effectively than conventional methods in rat liver S9 fractions, particularly at low testosterone levels.
12 citations
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April 2023 in “Nano Biomedicine and Engineering” This study synthesized silver nanoparticles using an Artocarpus heterophyllus leaf extract and found that these nanoparticles, with a size of 100–110 nm, displayed effective antioxidant, antibacterial, and antifungal activities in vitro.
January 2026 in “Journal of Nanomaterials” April 2018 in “DSpace@MIT (Massachusetts Institute of Technology)” Nephronectin is linked to worse outcomes in breast cancer and helps cancer spread.