TLDR Blocking testosterone action may improve breathing during NREM sleep in healthy men.
The study suggested that blocking the action of testosterone through the 5α-reductase pathway could improve breathing stability during non-rapid eye movement (NREM) sleep in healthy men. This finding indicated a potential new therapeutic approach for treating central sleep apnea in certain populations.
195 citations
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February 2007 in “The Journal of Clinical Endocrinology and Metabolism” Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.
31 citations
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January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
26 citations
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August 2014 in “PubMed” Testosterone improves mood and thinking skills; finasteride has no effect.
3 citations
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October 2015 in “Human Psychopharmacology-clinical and Experimental” Finasteride doesn't affect sleep spindles in men.
7 citations
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June 2020 in “Translational Andrology and Urology” Finasteride for hair loss may cause lasting sexual, genitourinary, mental, and anti-androgenic side effects in young men.
February 2025 in “International Journal of Impotence Research”
