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Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

New treatments for male hypogonadism are effective and should be personalized.

The document concludes that proper diagnosis and FDA-approved treatments for different types of hair loss exist, but treatments for severe cases often fail and future improvements may focus on hair follicle stem cells.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Some treatments, like corticosteroids and sensitizing agents, can help with alopecia areata, but more high-quality research is needed.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

New genes and pathways are important for testosterone production and male sexual development.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Some breast cancer chemotherapy can cause permanent hair loss.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

Neurosteroids show promise for treating epilepsy and more research is needed.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

LED therapy is safe and shows potential for treating skin conditions and promoting hair growth, but more research is needed.

Low iron and vitamin D levels are linked to hair loss in women.

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.

There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Both drugs lower DHT levels, with GI198745 being more effective.

Prostaglandin D₂ might be targeted for new male pattern baldness treatments.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Some women with acne have higher levels of free testosterone, which might suggest using hormonal treatments for acne.