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A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.

Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.

Dihydrotestosterone (DHT) increases oil production in skin cells by activating mTOR, and mTOR inhibitors can reduce this effect.

Young men with early baldness may have lower Luteinizing Hormone levels due to higher dihydrotestosterone, possibly linked to certain drugs or gland disorders.

Young men with early baldness may have lower Luteinizing Hormone levels due to higher dihydrotestosterone, possibly from certain drugs or gland disorders.

Testosterone and dihydrotestosterone can slow down the growth of certain hair follicle cells.

Male pattern baldness is mainly caused by a hormone called dihydrotestosterone (DHT), and drugs that can block this hormone might help prevent hair loss.

Different hair growth phases affect how follicles respond to X-rays, and hormones like testosterone and dihydrotestosterone play a key role in baldness; transplanted hair can grow on bald scalp areas.

New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.

Taking 1 mg finasteride for a year reduces dihydrotestosterone levels in men with early hair loss, but doesn't change their metabolic state.

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Androgens can both increase and decrease hair growth in different parts of the body.

Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

Prostate cancer was a major health issue in 2009, especially for Black men, and targeting the 5alpha-reductase enzyme could help in its prevention and treatment.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Spironolactone reduced hair thickness and some testosterone levels in women with excessive hair growth.

Finasteride effectively blocks enzyme causing male pattern baldness.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.