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11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Sebocytes play a key role in controlling androgen levels in human skin.

A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

Oleanolic acid improved hair growth in mice by affecting hair growth pathways and reducing inflammation.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Finasteride helps protect brain in old male rats.

Certain Dibenzo derivatives may help treat prostate cancer.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Finasteride safely lowers DHT levels without affecting testosterone.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Certain drugs that block specific enzymes can help treat prostate diseases.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.