31 citations
,
November 2022 in “Cold Spring Harbor Perspectives in Biology” This review explores how epithelial cells from various niches in the skin respond and adapt during acute wound repair, highlighting the role of cellular plasticity in reepithelialization and restoring the skin's barrier function.
21 citations
,
December 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that fibroblast behavior switching between proliferation and ECM deposition is vital for dermal architecture, where cell migration is primarily important for tissue repair during wound healing.
61 citations
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January 2013 in “International Journal of Biological Macromolecules” This study found that applying both dehydrothermal treatment and carbodiimide crosslinking improved the mechanical properties of porcine acellular dermal matrix scaffolds without added cytotoxicity, suggesting potential applications in tissue engineering.
June 2023 in “Juan Cuevas eBooks” This volume is part of a series intended to educate plastic and reconstructive surgeons, residents, and other medical professionals, but the abstract does not report specific research findings.
31 citations
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August 1986 in “Plastic & Reconstructive Surgery” This study found that using Dexon sutures led to significantly larger postoperative stretching and scar width compared to Prolene in patients undergoing scalp surgery for androgenetic alopecia correction.
65 citations
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March 2018 in “Journal of Dermatological Science” This review discusses the role of mechanical forces in skin homeostasis and disease development, including their impact on conditions like keloids, androgenetic alopecia, and acral melanoma, and reports no clinical results; the authors propose modifying these forces as a potential therapeutic strategy.
8 citations
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July 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the tensile strength of curly hair is influenced by two main components, with springiness (toe region) contributing significantly, unlike in noncurly hair where it is negligible.
1 citations
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September 2025 in “PLoS ONE” This study observed that in mouse fetuses, reticular contraction by actomyosin is involved in dermal regeneration, and differences in actin and α-SMA localization may determine the switch between regeneration and scar formation, suggesting potential insights for wound regeneration therapy.
479 citations
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June 2014 in “Science” This review discusses the plasticity of epithelial stem cells in regenerative contexts and reports no new research findings; the authors highlight potential implications for regenerative medicine and cancer.
3 citations
,
January 2022 in “Biomaterials Science” This study found that bioinspired conductive dressings with aligned wrinkles can monitor joint motion and significantly accelerate wound healing in mice by promoting collagen deposition, hair follicle regeneration, and epithelialization.
2 citations
,
July 2024 in “Materials Today Communications” In this study, an injectable alginate hydrogel with Fibronectin3 was developed, demonstrating high biocompatibility and ability to enhance wound healing in mice, suggesting promise for clinical application in treating irregular wounds.
7 citations
,
February 2009 in “Cell and tissue biology” July 2024 in “Journal of Investigative Dermatology” Pediatric patients with dystrophic epidermolysis bullosa face more hospital admissions, procedures, and complications than others.
1 citations
,
July 2025 in “Cancer Medicine” This study observed that colorectal cancer tumoroids adapted to an environment without a matrix by developing disordered self-assembly, but their tumor-specific phenotypes and drug sensitivity remained unchanged.
425 citations
,
January 2021 in “SN Applied Sciences” This article highlights the versatility and potential of alginate and its derivatives in tissue engineering applications, discussing their properties, modification techniques, and various uses in enhancing tissue healing, bone regeneration, and cell growth.
85 citations
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October 2007 in “International Journal of Dermatology” In this study, researchers found that the curliness of human hair is associated with an asymmetric structure at the cellular level, particularly in the differentiation of the precortex.
July 2026 in “Organoid Research” This review focuses on hydrogel microsphere-mediated strategies to improve organoid culture by addressing deficiencies in extracellular matrix organization, potentially enhancing the physiological accuracy and clinical translatability of osteomuscular in vitro models as reported in this study.
August 2026 in “Acta Biomaterialia” 1 citations
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June 2014 in “[Thesis]. Manchester, UK: The University of Manchester; 2014.” This study found that chemically modifying human hair through esterification or disulfide reduction and alkylation affects the hair's viscoelastic properties, including stability, integrity, and response to moisture.
1 citations
,
December 2022 in “Skin Research and Technology” This article provides guidelines and indices for a three-point cantilever bending test to measure mechanical properties of hair treated with both conventional and naturally-derived styling polymers, reporting no new experimental results.
1 citations
,
March 2005 in “International Journal of Cosmetic Science” Twisting hair weakens it, but strength can be recovered at low twist levels.
1 citations
,
June 2021 in “Computer methods and programs in biomedicine” This study found that children with cancer showed more deviation from typical facial morphology compared to healthy controls, although the differences were not enough to distinguish patients from controls based on facial asymmetry alone.
December 2025 in “Materials Technology” In this laboratory study, researchers developed a genipin-stabilized asymmetric PLA/gelatin scaffold that mimics skin architecture, supports fibroblast proliferation, and closes scratches effectively, suggesting its potential for epidermal-dermal regeneration and applications in sensing or drug delivery.
6 citations
,
April 2001 in “The Anatomical Record” This study introduces a method for determining the orientation of collagen fibers in skin by analyzing the anisotropic shape of hair pores, which may aid in skin grafting procedures.
11 citations
,
May 2016 in “PubMed” This article reviews various methods and introduces new imaging technologies to assess the effects of hair shaping treatments on hair chemistry and structural integrity, without reporting clinical results.
1 citations
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July 2024 in “International Journal of Cosmetic Science” This study validated a new tool for assessing curly hair manageability, finding that hair curvature is a key factor influencing hair practices and product attitudes among women with natural curly hair.
August 2022 in “Tissue Engineering Part A” This study observed that using ex vivo gene therapy to modify skin cells in a pre-graft model improved dermal-epidermal junction adhesion strength and maintained collagen production over time, suggesting a potential treatment approach for recessive dystrophic epidermolysis bullosa skin wounds.
239 citations
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December 2013 in “Scientific Reports” In this study, researchers developed a microfluidics-based method for creating uniform, size-controlled stem cell spheroids that enhance osteogenic differentiation when encapsulated in alginate-RGD microgels.
65 citations
,
August 2013 in “Acta Biomaterialia” This study suggests that a novel micropatterned dermal–epidermal matrix (μDERM) enhances keratinocyte function and epidermal morphology, offering potential improvements in skin substitute design for wound healing applications.
18 citations
,
February 2015 in “Acta Crystallographica Section D: Structural Biology” This study reports that Ca 2+ binding alters the dynamics and surface properties of PKD-like domains in Clostridium histolyticum collagenases, enhancing their stability and potentially aiding in collagen-targeting vehicle development.