October 2022 in “Hair Transplantation” This chapter reviews causes of poor scarring in hair restoration procedures and discusses methods for improving donor site scars, reporting no new clinical results.
January 2025 in “Indian Journal of Dermatology” This review discusses the various factors implicated in the etiology of frontal fibrosing alopecia and notes the need for effective treatments, reporting no new clinical findings.
August 2023 in “International journal of experimental research and review” This study found that in models of diabetic wound healing, extracts from the flavonoid and tannin fractions of Ficus racemosa leaves improved wound closure time, increased breaking strength of incision wounds, and exhibited hypoglycemic activity.
7 citations
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January 2019 in “Dermatology Online Journal” In this case report, a 62-year-old woman's persistent frontal fibrosing alopecia while on the psoriasis medication ustekinumab suggests that IL-12 and IL-23 inhibition may not be effective in treating this scarring alopecia, challenging the role of Th1 and Th17 pathways in its pathogenesis.
2 citations
,
April 2017 in “Actas Dermo-Sifiliográficas” This review discusses the etiology, pathogenesis, clinical presentation, and treatment of frontal fibrosing alopecia, noting the lack of clinical trial data and limited observational treatment results.
This review synthesizes evidence on strategies to preserve donor aesthetics and reserve in follicular unit extraction, emphasizing conservative extraction limits and long-term planning to prevent donor site morbidity.
3 citations
,
April 2015 in “Dermatology practical & conceptual” Postmenopausal women can experience hairline recession, affecting their quality of life, and more research is needed for treatments.
2 citations
,
January 1980 in “Archives of Dermatology” This letter discusses concerns about the term "telogen effluvium" and suggests using "telogen defluxion" instead, but reports no new results.
April 2019 in “Journal of Investigative Dermatology” Targeting immune pathways like JAK/STAT may help treat frontal fibrosing alopecia.
2 citations
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September 2021 in “Anais Brasileiros de Dermatologia” Increased sunscreen use may be linked to frontal fibrosing alopecia in Hispanic females.
February 2004 in “Dermatologic Surgery” This study found that deep plane fixation in scalp surgeries allowed for tension-reduced wound closures and increased tissue excision compared to techniques without deep plane fixation.
March 2025 in “Revista Foco” This review describes the clinical signs, symptoms, and diagnostic findings for alopecia frontal fibrosante, emphasizing the importance of early diagnosis and variable treatment options, and reports no new findings.
4 citations
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June 2017 in “Annales de dermatologie et de vénéréologie” This prospective study in Morocco reported on 20 cases of frontal fibrosing alopecia, finding that dermoscopy played a key role in diagnosing and managing the condition, which can increasingly affect premenopausal women.
5 citations
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January 2022 in “Molecular Medicine Reports” In this study, topical application of Korean maritime pine bark extract at 2% concentration significantly promoted hair growth in mice, suggesting its potential use for hair loss prevention or treatment.
23 citations
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October 2018 in “Australasian Journal of Dermatology” This review highlights that frontal fibrosing alopecia’s increasing incidence may involve immune, genetic, hormonal, and environmental factors, yet its pathogenesis remains complex and not fully understood.
March 2025 in “GSC Biological and Pharmaceutical Sciences” In this review, the authors examined the potential benefits of using wood tar in dermatology and cosmetics in Sub-Saharan Africa, based on its historical application in skin care and its worldwide usage.
December 2023 in “Dermatologic Surgery” The researchers reported that using a skin-responsive FUE device in nonscalp hair transplantation significantly reduced graft transection rates compared to older methods, improving patient satisfaction and surgeon willingness.
2 citations
,
May 2018 in “PubMed” In this study, hair restoration using follicular unit extraction removed about 35% of donor area hair density, indicating a need for careful consideration of varying donor densities.
325 citations
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June 1994 in “Archives of Dermatology” This study observed that progressive frontal recession in postmenopausal women may exhibit features of fibrosing alopecia, suggesting a distinct reaction pattern from typical lichen planopilaris.
January 2025 in “Revista del Centro Dermatológico Pascua” Early diagnosis and treatment can help manage fibrosing alopecia in older women.
2 citations
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June 2024 in “Skin Appendage Disorders” This study identifies specific trichoscopic features such as empty follicles and perifollicular erythema in Caucasians with frontal fibrosing alopecia, which may assist in diagnosis and monitoring, but stresses the need for further research due to limited demographic data.
1 citations
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March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that Dermal Fibroblast Progenitors have repressed chromatin profiles which hinder their ability to reform skin in allograft assays despite their differentiation potential.
September 2024 in “Cutis” Sunscreen use may increase the risk of frontal fibrosing alopecia.
April 2021 in “Journal of Investigative Dermatology” Blocking DPP4 can help prevent fat loss and skin fibrosis.
May 2019 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This study reviewed 38 cases of frontal fibrosing alopecia, observing that diagnosis often occurs years after onset and is more prevalent in postmenopausal women.
1 citations
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July 2021 in “Dermatologic Surgery” This study found that follicular de-epithelialization in follicular unit extraction does not impact graft survival rates but may improve immediate postoperative appearance and cosmetic satisfaction.
13 citations
,
December 2017 in “CNS Neuroscience & Therapeutics” In this study, finasteride was found to inhibit the dopaminergic system and reduce open-field behaviors in adolescent male rats by decreasing dopamine levels and related proteins.
23 citations
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May 2017 in “Journal of the American Academy of Dermatology” This study found that patients with frontal fibrosing alopecia had lower epidermal melanocyte counts and reduced epidermal thickness compared to lichen planopilaris patients and controls, suggesting a link with hypopigmentation.
This study found that depleting fibroblasts in the skin does not affect the proliferative capacity of epidermal stem cells at various ages, suggesting robust compensatory mechanisms maintain skin functionality despite these cellular changes.
2 citations
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January 2010 in “PubMed” This case report observed no hair regrowth after treating a woman with postmenopausal frontal fibrosing alopecia using systemic and local corticosteroids, suggesting the need for more innovative therapies.