Fibroblast Depletion Reveals Mammalian Epithelial Resilience Across Neonatal and Adult Stages

May 2026

Isabella Gaeta, Shuangshuang Du, Clémentine Villeneuve, David G. Gonzalez, Catherine Matte-Martone, Smirthy Ganesan, David Simpson, Jessica L. Moore, Chen Yuan Kam, Sara Gallini, Haoyang Wei, Fabien Bertillot, Dagmar Zeuschner, Lauren E. Gonzalez, Kaelyn Sumigray, Sara A. Wickström, Valentina Greco

Studysummary This study found that depleting fibroblasts in the skin does not affect the proliferative capacity of epidermal stem cells at various ages, suggesting robust compensatory mechanisms maintain skin functionality despite these cellular changes.

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Fibroblast Depletion Reveals Mammalian Epithelial Resilience Across Neonatal and Adult Stages

Research cited in this study

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