Steven Kossard's Postmenopausal Frontal Fibrosing Alopecia: A Therapeutic Dilemma

    January 2010 in “ PubMed ”
    Georgi Tchernev, Michael Tronnier
    TLDR Current treatments for postmenopausal frontal fibrosing alopecia stop hair loss but don't regrow hair.
    Steven Kossard identified a type of hair loss called postmenopausal frontal fibrosing alopecia (PFFA), characterized by a symmetric regression of the frontal hairline and often affecting the eyebrows, with histology showing lichen planopilaris. The condition was primarily observed in elderly women. In a reported case, systemic and local corticosteroid therapy halted disease progression, but no hair regrowth was observed over a 6-month period. Although a hormonal basis was not proven, finasteride's effectiveness in some cases suggested a potential androgenic role. Corticosteroids did not achieve permanent remission or hair regrowth, indicating a need for more innovative treatments, such as skin transplantation and 5-alpha reductase blockers, which were effective in male androgenetic alopecia.
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