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In this study, Wharton’s Jelly Mesenchymal Stem Cells, cultured with human platelet lysate, showed enhanced wound-healing capabilities and multilineage differentiation potential, distinguishing them from bone marrow-derived stem cells and presenting exciting prospects for regenerative medicine.

In this study, collagen I decellularized scaffolds enhanced the growth and melanotic properties of hair follicle melanocytes, suggesting their potential as effective carriers for transplantation in vitiligo treatment.

In this study, exosome-loaded hydrogels derived from skin precursor cells significantly improved wound healing in diabetic rats by enhancing angiogenesis, reducing inflammation, and promoting tissue repair.

In this study, researchers developed a 3D in vitro model using decellularized Dupuytren’s disease tissue seeded with patient-derived fibroblasts, providing a platform to test antifibrotic therapies like minoxidil and demonstrating more complex drug responses than traditional 2D cultures.

This study suggested that non-colony dissociated hiPSCs can be effectively differentiated into functional RPE cells, and hiPSC-RPE cell spheroids showed promise for use in subretinal transplantation in animal models of retinal degeneration.

This study reported that in degenerative alopecia, Zn²⁺/Cu²⁺-dependent proteases are downregulated and destabilized, and a specially developed microneedle patch reactivated these enzymes, reduced senescence, and enhanced hair regeneration in an animal model.

This study found that a mesenchymal stromal cell-derived regenerative extracellular matrix (rECM) significantly accelerated wound closure and improved healing in diabetic mice, also enhancing nerve and blood vessel formation compared to controls.

This study demonstrated that a new biomimetic tissue engineering strategy using DP spheroids with vascularization significantly restored the hair-inducing properties of dermal papilla cells compared to traditional 3D cultures.

This study reports that transplantation of an ESCs-collagen-chitin biomimetic membrane leads to successful in situ skin regeneration, including hair follicle cell proliferation and formation of dermatoglyphs, in nude mice with full-thickness skin defects.

This study found that a 3D co-culture of adipose-derived stem cells and endothelial colony forming cells restored stem cell properties and enhanced wound healing in a mouse model.

In this study, the researchers reported that using a biodegradable ECM scaffold for large-area wound regeneration accelerated wound coverage and improved hair follicle neogenesis by activating the adaptive immune system.

This study found that a 3D co-culture of endothelial colony-forming cells and adipose-derived stem cells restored stem cell properties and improved healing in a mouse model of chronic injury.

This study found that electrospun short fibrous sponges effectively mimic the 3D extracellular matrix, promoting tissue regeneration, angiogenesis, and wound healing in diabetic rats better than 2D fiber membranes.

This research observed that 3D electrospun micro/nanofibrous sponges, without using chemical crosslinking agents, supported enhanced cell growth, vascularization, and skin regeneration in diabetic rats compared to 2D fiber membranes, making them promising for 3D tissue regeneration.

This study observed that ECMs produced by papillary fibroblasts showed the largest fibers and supported keratinocyte differentiation better than reticular fibroblast matrices, informing biomimetic material design for skin tissue engineering.

This study found that a hydrogel made from human placenta-derived ECM, copper, and endothelial progenitor cells significantly enhanced pressure ulcer healing in a mouse model by improving wound closure and tissue regeneration.

In this study, researchers modified an acellular scaffold with different concentrations of eggshell membrane protein, finding that a 5% concentration effectively enhanced tissue regeneration in mice with excisional wounds, achieving complete healing within 14 days without causing immunogenicity or inflammation.

In this study, researchers used a 3D printing technique to spatially pattern human dermal papilla cell spheroids in a collagen matrix, enhancing skin and hair regeneration in a mouse model, with notable upregulation of key genes for hair follicle formation compared to traditional cell cultures.

In this study, researchers developed a new SFL-3D system to produce extracellular vesicles from rejuvenated dermal papilla cell spheroids, which demonstrated significant antifibrotic effects in reducing hypertrophic scarring, highlighting their potential for precision-targeted scar management.

This study reports that tissue-engineered skin using ES cell-derived epidermal stem cells and collagen sponge successfully healed full thickness skin defects in mice, forming epidermis and structures resembling glands and hair follicles.

This study developed a protocol for acellular dermal matrix manufacturing from pig skin, demonstrating effective removal of cellular components while preserving the collagen scaffold's structural organization through a series of physical and chemical treatments.

This special issue reviews advancements in engineering cell microenvironments for tissue engineering, highlighting various studies on interventions like silk fibroin and platelet-rich plasma, but presents no new empirical findings.

This study found that applying both dehydrothermal treatment and carbodiimide crosslinking improved the mechanical properties of porcine acellular dermal matrix scaffolds without added cytotoxicity, suggesting potential applications in tissue engineering.

This study introduced a novel 3D co-culture system that effectively mimics in vivo extracellular matrix dynamics, supporting hair follicle biology research and providing a robust platform for evaluating hair loss treatments through enhanced epithelial-mesenchymal interactions.

This study developed a 3D skin model with immune and endothelial cells, which may enhance understanding of skin biology and diseases due to its closer approximation to native skin.

In this study, a bioengineered construct using a biodegradable polycaprolactone mat cocultured with human keratinocyte and rabbit dermal fibroblast cells demonstrated potential as a tissue-engineered skin substitute, showing good cell adhesion and growth.

This study found that murine epidermal stem cells implanted subcutaneously in a biodegradable carrier could survive and differentiate into structures resembling native dermis without significant rejection in recipient mice.

This study found that a new-type artificial xenogenic derma exhibited better biocompatibility and dermal tissue regeneration ability compared to cross-linked acellular dermal matrix in a mouse model.

This study found that engineered reconstituted skin can form morphogenetic units that promote tissue patterning and hair regeneration, with certain signaling pathways restoring this ability in adult and fetal cells.

This study found that microporous electrospun scaffolds with a 70:30 collagen I to poly(ɛ-caprolactone) ratio significantly accelerated wound closure and dermal regeneration in full-thickness critical-sized skin defects.