Development of a 3D In Vitro Model of Dupuytren’s Disease as a Platform for Drug Screening
January 2026
in “
Cellular and Molecular Bioengineering
”
Studysummary In this study, researchers developed a 3D in vitro model using decellularized Dupuytren’s disease tissue seeded with patient-derived fibroblasts, providing a platform to test antifibrotic therapies like minoxidil and demonstrating more complex drug responses than traditional 2D cultures.
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