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The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.

Stauntonia hexaphylla extract can help treat hair loss by blocking certain hormones.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Padina arborescens and its component MOGG may help prevent hair loss through several actions, including blocking a hair loss-related enzyme.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.

Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

TGF-alpha is present in sheep and ferret skin and may affect hair growth without directly stimulating cell proliferation.

5-alpha-reductase inhibitors significantly affect the penile tissue of hypertensive rats.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.

A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

IL-1 alpha stops hair follicle growth and hair production.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

Finasteride works better than Permixon in reducing dihydrotestosterone levels.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

Most patients treated with low-dose alpha-interferon for malignant melanoma experienced skin side effects, with hair loss being the most frequent.

Finasteride and minoxidil together promote hair growth better than either alone.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.

Finasteride reduces hair growth and is safe for women with excessive hair.

Finasteride doesn't affect hormone levels in normal men.

17α-Estradiol solution safely improves hair density and thickness in female pattern hair loss.

5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.

No link found between specific genes and female pattern hair loss.