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    Glossary Cytokine Storm

    overactive immune response releasing excessive cytokines, causing severe inflammation

    A Cytokine Storm, also known as Cytokine Release Syndrome (CRS), is a severe immune reaction where the body releases an excessive amount of cytokines into the blood too quickly. This overproduction can lead to widespread inflammation, tissue damage, and potentially organ failure. It is often seen in severe infections, certain autoimmune conditions, and as a side effect of some immunotherapies.

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    1. Olink proteomics analysis of scalp psoriasis reveals a cytokine storm inflammatory mainly related to bacterial-derived antigens 2025
    2. COVID-19 and Sex Differences Mayo Clinic Proceedings · 2020 · 185 citations
    3. Are the cutaneous manifestations during or due to SARS-CoV-2 infection/COVID-19 frequent or not? Revision of possible pathophysiologic mechanisms Inflammation Research · 2020 · 82 citations
    4. Telogen effluvium related to post severe Sars‐Cov‐2 infection: Clinical aspects and our management experience Dermatologic Therapy · 2020 · 35 citations
    5. COVID-19 infection is a major cause of acute telogen effluvium Irish Journal of Medical Science (1971 -) · 2021 · 25 citations
    6. Testosterone target therapy: focus on immune response, controversies and clinical implications in patients with COVID-19 infection Therapeutic Advances in Endocrinology and Metabolism · 2021 · 21 citations
    7. Pathobiology questions raised by telogen effluvium and trichodynia in COVID‐19 patients Experimental Dermatology · 2021 · 18 citations
    8. Early-onset effluvium secondary to COVID-19: Clinical and histologic characterization Journal of The American Academy of Dermatology · 2021 · 7 citations
    9. Black dots in trichoscopy after COVID‐19. Can it be telogen effluvium? Dermatologic Therapy · 2021 · 2 citations
    10. Manifestaciones dermatológicas asociadas a la gravedad de la infección por COVID-19. Estudio observacional transversal retrospectivo de 144 pacientes Piel · 2022 · 1 citations
    11. Editor's Picks August 2023 Journal of the European Academy of Dermatology and Venereology · 2023
    12. Self-Reported Hair Loss Following COVID-19: An Observational Study International Journal of Dermatology and Venereology · 2023
    13. Telogen Effluvium and COVID-19: a case and a brief review of literature Medicina · 2022
    14. Telogen Effluvium and COVID-19 DOAJ (DOAJ: Directory of Open Access Journals) · 2022
    15. Free Testosterone Levels in Patients with Covid-19 and its Association with Disease Severity International journal of respiratory and pulmonary medicine · 2022
    16. Weathering the Storm: Harnessing the Resolution of Inflammation to Limit COVID-19 Pathogenesis Frontiers in Immunology · 2022 · 17 citations
    17. The Potential of Cannabidiol for Acute Respiratory Distress Syndrome inCOVID-19 Current Pharmaceutical Design · 2023
    18. Minoxidil Promotes Hair Growth in a Mouse Model of Telogen Effluvium Induced by Lipopolysaccharide The Journal of Dermatology · 2025
    19. Taming of Covid-19: potential and emerging application of mesenchymal stem cells Cytotechnology · 2021 · 6 citations
    20. Extrapulmonary manifestations of coronavirus disease (COVID-19): current status (a literature review) Zaporozhye Medical Journal · 2022 · 2 citations
    21. From causes of aging to death from COVID-19 Aging · 2020 · 122 citations
    22. The effect of canakinumab on clinical outcomes in patients with COVID-19: A meta-analysis Journal of Infection · 2022 · 19 citations
    23. Large Screening Identifies ACE2 Positively Correlates With NF-κB Signaling Activity and Targeting NF-κB Signaling Drugs Suppress ACE2 Levels Frontiers in Pharmacology · 2021 · 13 citations
    24. The impact of certain genetic variants (single nucleotide polymorphisms) on incidence and severity of COVID‐19 ˜The œjournal of gene medicine · 2021 · 7 citations
    25. An outline of SARS-CoV-2 pathogenesis and the complement cascade of immune system 2021 · 6 citations
    26. Dermatological Manifestations of COVID-19: A Comprehensive Review Physician s Journal of Medicine · 2025
    27. Cytokine loaded layer-by-layer ultrathin matrices to deliver single dermal papilla cells for spot-by-spot hair follicle regeneration Journal of Materials Chemistry B · 2015 · 19 citations
    28. Adverse cutaneous reactions to chemotherapeutic agents and cytokine therapy Seminars in Cutaneous Medicine and Surgery · 1996 · 18 citations
    29. Cytokines Clinics in Dermatology · 1996 · 3 citations
    30. Aged differentiated cells reverse into native stemness-like state by niche cytokines to sustain lifelong homeostasis and tissue repair Nature Communications · 2026