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Scientists found a new gene in a bacterium that can modify an immunosuppressant drug, potentially helping to treat hair loss.

The authors suggest that 5-α-reductase inhibitors, like dutasteride, are effective in treating frontal fibrosing alopecia and should be the first-line treatment, with other options for severe cases. They also recommend further research on Janus kinase inhibitors.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

Adding soybean oil to Nonomuraea dietziae increases production of a beneficial compound by improving metabolism and enzyme systems.

Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.

The traditional herbal formulas Yongdamsagan-Tang and Paljung-san, along with the drug finasteride, can reduce inflammation and may work together without affecting each other's effectiveness against benign prostatic hyperplasia.

Saw palmetto can help with prostate issues and may promote hair growth.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

Teriflunomide is effective and generally safe for treating relapsing-remitting multiple sclerosis.

A woman developed Cushing syndrome and adrenal insufficiency from using fluticasone and ritonavir together.

Finasteride metabolism varies by age, sex, and P450 inducers, with males processing it faster.

Scientists improved an enzyme to better produce a hair growth-promoting chemical from an immunosuppressant.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

A new method can almost perfectly distinguish adenomyosis from similar conditions using blood tests.

The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.