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The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Women with androgenic alopecia are more likely to have polycystic ovaries and higher androgen levels, which may indicate PCOS.

Skin grafting can help repigment vitiligo, but it's less effective for widespread cases due to the Koebner phenomenon.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Coats' Plus is a genetic disorder with eye abnormalities, brain calcification, poor growth, bone and skin issues, and movement disorders.

Correcting nutrient deficiencies may help with hair loss, but the benefits of supplements without a deficiency are uncertain and could be harmful.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

Polycystic ovarian shape is a genetic sign of PCOS and its hormonal and metabolic features can be inherited.

Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

Advanced human skin models improve drug development and could replace animal testing.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Women with PCOS often feel stigmatized and have mood issues, which can lower their sexual satisfaction, but proper treatment and support can help.

Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.

Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.