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Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.

Older women's scalp cells show changes that could contribute to hair thinning.

Skin tumor cells in patients with tuberous sclerosis have higher levels of a protein called cathepsin B.

Afatinib, neratinib, and zanubrutinib could be effective against KRASG12C-mutant tumors.

Certain compounds found in edible mushrooms may help treat hair loss.

Targeting the PGD2-DP2 pathway may help treat hair loss.

Both sildenafil and minoxidil effectively treat male hair loss, but impact hair differently.

Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.

Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.

Keratin from hair and wool is used in medical materials for healing and drug delivery.

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

Hydrogel scaffolds can help wounds heal better and grow hair.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.

Reactive oxygen species (ROS) help control plant growth and development.

Human hair is made up of different keratins, some strong and some weak, with specific types appearing at various stages of hair growth.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

New treatments for PCOS show promise, including both medication and non-medication options.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

Wnt signaling is crucial for skin development and hair growth.

Metabolic signals and cell shape influence how cells develop and change.

Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.

Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.