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This study found that in mice, competition for hair follicles guides the organization of follicle-innervating LTMR neurons during early development, with different neuronal subtypes showing varying adaptive responses to increased neuron populations.

This study found that colchicine treatment significantly reduced hair fiber elongation in cultured hair follicles and altered protein expression and activity in dermal papilla cells, suggesting a role for the ubiquitin-proteasome system in its effects.

This review summarized and classified 32 approved synthetic and natural-identical antioxidants, examining their regulatory status, safety, pharmacological properties, and effectiveness on human health, aiming to clarify their antioxidant actions and encourage further research in the field.

This study found histopathological evidence of hypertrophy in nerve endings that may explain the cutaneous neurosensory symptoms in some long COVID-19 patients.

SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.

This study investigated the photoprotective properties of Brazilian pepper tree extract against UV-induced damage in skin cells, reporting that it enhanced expression of genes relevant to skin health and showed superior activity compared to standard antioxidants.

This review explains that dysregulated sebum secretion and composition contribute to acne and impaired skin barriers while highlighting factors like diet and hormones affecting sebaceous activity, and identifies novel molecular targets and model systems for future therapeutic developments.

This study found that procyanidin oligomers, particularly dimers and trimers, significantly promoted hair growth in mice and hair epithelial cell cultures, suggesting potential use as hair growth agents.

This review summarizes current knowledge on the efficacy of natural molecule supplementation, such as inositols and omega-3 fatty acids, in managing PCOS symptoms but reports no new clinical results.

This study found that bee venom accelerated the transition from the telogen to anagen phase in mice, increasing hair growth by day 14, and suggested that bee venom may enhance adipose-derived stem cell activity by upregulating growth factor secretion.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

This study found that dermatoses are common in people living with HIV and may serve as indicators of disease stage, with certain conditions more prevalent when CD4+ counts are below 200/mm³.

This study found that newborn mouse skin organoids can robustly grow hair in vivo, while adult organoids require specific interventions to restore their hair-forming ability.

Accidental findings have led to new hair treatment discoveries, like using blood pressure and diabetes medications for hair loss and unwanted hair.

In this experimental study on Holtzman rats with induced benign prostatic hyperplasia, the researchers observed that the extract of Physalis peruviana (aguaymanto) had a greater therapeutic effect on prostate weight reduction and prostatic epithelium height compared to finasteride and terazosine.

This study demonstrated that disrupting sonic hedgehog signaling, using cyclopamine, significantly impaired wound healing in a mouse model, suggesting its crucial role in postnatal tissue repair.

This study found that the cyanoacrylate biopsy method could effectively evaluate drug distribution in hair follicles, suggesting its potential utility for assessing topically applied chemicals targeting hair follicles.

This review discusses how the nuclear lamina integrates biochemical and mechanical signals to influence gene expression and skin homeostasis, but reports no new clinical results.

This study found that interleukin-1-alpha and oncostatin-M levels were positively associated with PCOS development, while interleukin-7, IL15RA, and CXCL11 were negatively associated, suggesting a connection between inflammatory factors and PCOS.

This study found that using a standardized protocol with microspheres of approximately 1.5 micrometers enhances penetration into hair follicles, particularly when skin is treated with cyanoacrylate skin surface stripping.

This study introduces a novel non-invasive method called "differential stripping" to quantify the penetration of topically applied substances into hair follicles.

This article discusses methods to measure comedogenesis in acne through the presence of microcomedones and reports no new clinical results; the authors outline a skin surface biopsy technique using cyanoacrylate gel.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

This report describes a case in which intramuscular cyanocobalamin treatment reversed skin and nail pigmentation changes and premature gray hair caused by vitamin B12 deficiency due to pernicious anemia.

This narrative review discusses the use of cyclosporin for various skin diseases in small animals and notes minimal side effects at therapeutic doses, but reports no original clinical findings.

In this study, cyclosporin A treatment significantly increased hair length in nude mice compared to controls, but hair growth reversed after treatment stopped.

This study suggests that topical Cyclosporin A formulations, with or without a penetration enhancer, effectively stimulated hair regrowth in a rat model of alopecia areata.

This article reviews the use of cyclosporine in dermatological conditions, noting its benefits in treating various skin diseases despite known adverse effects like nephrotoxicity and hypertension, and highlights its preferred use over other immunosuppressants due to an early therapeutic response and a good safety profile.

This study quantifies the follicular uptake of tea tree oil in bovine udder skin, with microemulsion showing the highest concentration among different formulations tested.

This pilot study suggests that topical cyclosporin may delay hair shedding and potentially treat alopecia, based on observations in a human scalp skin graft model on mice.