35 citations
,
December 2020 in “International Journal of Molecular Sciences” This review examines the mixed evidence on mast cells as regulators of skin fibrosis and highlights existing gaps in the scientific understanding, reporting no new experimental results.
35 citations
,
October 2017 in “Signal Transduction and Targeted Therapy” This study found that fibromodulin significantly reduces scar formation and boosts scar strength in rodent and porcine models, suggesting potential for FMOD-based therapies in cutaneous wound repair.
35 citations
,
February 2004 in “Veterinary Dermatology” This study observed that cutaneous lymphocytosis in cats is a slowly progressive and relatively benign disease, but predicting individual clinical outcomes from skin lesions was not possible.
34 citations
,
February 2012 in “American Journal of Dermatopathology” This study found that calretinin immunoreactivity may help identify the innermost cell layer of the outer root sheath in anagen hair follicles and certain cutaneous adnexal proliferations with follicular, sebaceous, and eccrine differentiation.
34 citations
,
September 2009 in “International Journal of Dermatology” This article reviews the skin effects of anabolic-androgenic steroid use in athletes but reports no clinical results.
34 citations
,
November 1974 in “Archives of Dermatology” This report discusses historical cases of visual side effects from scalp corticosteroid injections for alopecia areata and attributes their rarity now to improved injection techniques and smaller particulate sizes in suspensions.
33 citations
,
March 2018 in “Italian Journal of Dermatology and Venereology” This article reviews clinical and histopathological aspects of cutaneous lupus erythematosus and its treatment, emphasizing the importance of photoprotection and outlining current therapies, but reports no new experimental results.
33 citations
,
April 2002 in “Journal of Cutaneous Medicine and Surgery” This review discusses the skin conditions linked to eating disorders and emphasizes that treating the underlying disorder often improves these dermatological symptoms.
32 citations
,
May 2018 in “Journal of the American Academy of Dermatology” This review describes how cutaneous toxicity from kinase inhibitors, immune checkpoint inhibitors, and chemotherapeutics could potentially serve as a biomarker for anticancer treatment efficacy, but highlights the need for more extensive research to confirm this association.
32 citations
,
January 2010 in “Journal of Dermatological Science” In this study, Waved-5 mice with reduced EGFR signaling showed nearly normal skin and hair follicle function but experienced a transient reduction in subcutaneous fat.
32 citations
,
September 1989 in “Medical Clinics of North America” This review describes the types of skin lesions associated with systemic lupus erythematosus, discussing their histopathological features, serologic associations, pathogenesis, and prognostic implications.
31 citations
,
December 2022 in “Cold Spring Harbor Perspectives in Biology” This review discusses the concept of epithelial-mesenchymal plasticity in wound healing and highlights restricting EMT for effective reepithelialization, but reports no new clinical results.
31 citations
,
March 2014 in “Journal of the European Academy of Dermatology and Venereology” In this study, multiple cutaneous adverse effects were observed in patients with metastatic malignant melanoma receiving BRAF inhibitors, but most were well managed with appropriate treatment.
31 citations
,
September 2012 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that proper levels of retinoic acid, controlled by the enzyme Cyp26b1, are essential for normal hair follicle development and morphogenesis in mice.
31 citations
,
January 2009 in “Autoimmunity Reviews” This study suggests that damage to stem cells in the bulge region of hair follicles may contribute to scarring in chronic cutaneous lupus erythematosus.
30 citations
,
January 2024 This review explores and updates previous findings on the skin manifestations associated with diabetes, questioning some established signs while introducing additional cutaneous symptoms linked to the condition.
30 citations
,
August 2021 in “Oncogene” This study reports that miR-22 promotes cancer progression and metastasis by maintaining Wnt/β-catenin signaling and cancer stem cell function.
29 citations
,
March 2023 in “The Journal of Dermatology” In this study, 16% of patients on dupilumab for atopic dermatitis experienced mild cutaneous adverse events, most commonly facial redness and psoriasis, leading to discontinuation in about 3% of cases.
29 citations
,
November 2014 in “Experimental Dermatology” This study found that α-MSH administration before skin wounding in adult mice reduced inflammation and scar area, suggesting a potential pathway to more regenerative healing.
29 citations
,
January 2012 in “Chemical immunology/Fortschritte der Allergielehre/Progress in allergy/Chemical immunology and allergy” This review discusses the various skin, mucosa, and adnexa side effects associated with different chemotherapeutic agents and provides insights into their clinical presentation and management; it reports no new results.
28 citations
,
January 2018 in “Biochemical Society Transactions” This review explores the role of fatty acids and bioactive lipid mediators in skin health and suggests targeting this metabolic network to control inflammation and improve skin conditions, but it reports no new findings.
28 citations
,
January 2017 in “Indian Dermatology Online Journal” In this study, skin manifestations such as hirsutism and acne were prevalent among women with PCOS, highlighting their importance in diagnosis and symptomatology.
28 citations
,
September 2014 in “Journal of Veterinary Internal Medicine” This study found that the novel drug VDC-1101 showed a 45% objective response rate in treating canine cutaneous T-cell lymphoma, offering a potential treatment option for this challenging disease.
28 citations
,
September 2002 in “The Journal of Comparative Neurology” This study found that presynaptic inhibition of Aαβ cutaneous primary afferents in cats is mostly mediated by GABAergic interneurons that also contain glycine.
28 citations
,
June 1995 in “The Journal of Dermatology” This study reports that flaky skin mice exhibit skin and nail features that closely resemble human psoriasis vulgaris, suggesting they may serve as a natural model for this condition.
27 citations
,
February 2009 in “Autoimmunity Reviews” This study describes the development of the EUSCLE Core Set Questionnaire for cutaneous lupus erythematosus, designed to standardize data collection, facilitate epidemiological analysis, and guide diagnostic and therapeutic strategies across European centers.
26 citations
,
January 2020 in “Dermatology Online Journal” This study found that livedoid and acro-ischemic skin manifestations were significantly associated with severe COVID-19, while chilblains-like eruptions appeared in less severe cases.
26 citations
,
May 2019 in “Journal of Multidisciplinary Healthcare” This review explores the epidemiology, clinical subtypes, pathology, psychological impact, and treatment options for cutaneous lupus erythematosus, emphasizing the importance of interdisciplinary collaboration and addressing psychological distress to optimize patient outcomes.
26 citations
,
October 2018 in “Clinical & Translational Oncology” This review outlines dermatological toxicities associated with targeted cancer therapies and immunotherapies, emphasizing the need for collaborative management by oncologists and dermatologists but reports no new clinical findings.
26 citations
,
November 2012 in “Clinics in Plastic Surgery” This article reviews treatments focused on stimulating collagen synthesis and improving skin appearance through methods like mechanical dermabrasion and laser surgery, but it reports no new clinical results.