9 citations
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June 2020 in “JAAD Case Reports” This article discusses dissecting cellulitis of the scalp, an uncommon hair condition, and reports no new clinical results; recent terminology adjustments are noted for potential overlaps with other follicular diseases.
32 citations
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November 2020 in “Nanomaterials” This study found that excipients significantly influence the effectiveness of curcumin nanocrystals in dermal applications, enhancing or hindering hair follicle targeting and passive diffusion based on their selection.
9 citations
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June 2017 in “Pharmacological Reports” This study found that ATP-sensitive potassium channels may play a role in chloroquine-induced itching in mice, as channel openers reduced scratching behavior while a blocker reversed these effects.
This source provides an overview of quercetin's therapeutic capabilities in skin wound healing, highlighting its antioxidant and anti-inflammatory benefits but noting its poor solubility limits skin penetration; various delivery strategies have been explored to enhance its effectiveness.
April 2023 in “Journal of Investigative Dermatology” This study suggests that the CsA-induced inactivation of the CaN/NFAT pathway may suppress TGF-β2 expression in dermal papilla cells, potentially contributing to CsA-associated hypertrichosis.
118 citations
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January 1992 in “Experientia” January 2025 in “Dermatological Reviews” This study reports that Cyperus rotundus L. (nut grass) shows promise as a natural hair removal agent, with compounds targeting hair follicles and potentially offering an alternative to chemical depilatories, demonstrated by its efficacy in clinical trials and comparable results to some laser treatments.
132 citations
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April 2007 in “European journal of pharmaceutics and biopharmaceutics” This study found that an oil-in-water microemulsion of curcumin penetrated deeper into the human stratum corneum and hair follicles compared to an amphiphilic cream.
1 citations
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January 2014 This study found that Crataegus pinnatifida extract promoted hair growth in mice by inducing the anagen phase, potentially through activating signaling pathways that enhance cell survival.
November 2016 in “The Molecular Biology Society of Japan”
April 2017 in “Journal of Investigative Dermatology” This study found that SM04755, a novel topical drug, inhibited inflammation, keratinocyte proliferation, and fibrosis in vitro and improved skin health in a mouse model of psoriasis, indicating potential as a topical psoriasis treatment.
October 2022 in “CRC Press eBooks” This review explores the botany, traditional uses, phytochemicals, and pharmacological activities of Cinchona pubescens but presents no new clinical findings.
15 citations
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November 2020 in “Pharmaceutics” In this ex vivo and mouse model study, Tofacitinib-loaded nanoparticles demonstrated enhanced delivery of the drug into hair follicles and reduced inflammatory effects compared to conventional forms, indicating potential for safer, topical use in treating alopecia areata.
2 citations
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January 2001 in “Dermatologic Surgery” This study concluded that poliglecaprone 25 sutures may result in less postoperative discomfort and narrower scar formation compared to metal staples in hair transplantation donor site closures.
April 2021 in “Research Square (Research Square)” This study found that the new cocrystal formulation KET-PABA improved the antimycotic efficiency of ketoconazole and induced an anti-inflammatory response without causing skin sensitization in mice.
December 2024 in “Naunyn-Schmiedeberg s Archives of Pharmacology” 2 citations
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October 2021 in “Clinical and experimental dermatology” In this study, Cyperus rotundus essential oil was found to have significantly better depigmenting effects than hydroquinone for treating axillary hyperpigmentation, with additional benefits in reducing inflammation and hair growth, making it a cost-effective and safe treatment option.
9 citations
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June 2021 in “Nutrients” In this study, fisetin applied to the dorsal skin of mice activated hair follicle stem cells through exosome secretion from keratinocytes, promoting hair growth.
9 citations
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January 2009 in “Journal of the European Academy of Dermatology and Venereology” This study found that a cream containing 6.0% Stryphnodendron adstringens bark extract effectively reduced terminal hair growth and improved skin conditions in women with excessive terminal hair.
2 citations
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September 2020 in “Swedish Journal of BioScience Research” This study found that chitosan from Lucilia cuprina improved burn healing in diabetic mice, promoting wound closure, epidermal remodelling, and collagen deposition, while also demonstrating antibacterial properties.
21 citations
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August 2002 in “British Journal of Ophthalmology” This article discusses topical and intralesional cidofovir use for SCC and suggests a successful outcome in one case, with no systemic toxicity observed so far.
75 citations
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June 2019 in “International Journal of Molecular Sciences” This review discusses the therapeutic potential of costunolide for various diseases, highlighting its bioactivity and mechanisms, but it reports no new experimental results.
19 citations
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January 2016 in “Biological & Pharmaceutical Bulletin” This study found that Sargassum muticum extract and apo-9′-fucoxanthinone promoted hair growth in rat and mouse models by increasing dermal papilla cell proliferation and activating certain signaling pathways.
November 2022 in “Journal of Investigative Dermatology” This study reported that an HS-associated NCSTN mutation in iPSC-derived skin organoids led to altered hair follicle stem cell differentiation and increased expression of proteins linked to HS inflammation.
January 2010 in “Journal of Animal Science” This study demonstrated that transcutaneous vaccination via cyanoacrylate skin surface stripping effectively induced both CD4 and CD8 T cell responses in humans, offering a promising alternative to intramuscular injection.
April 2026 in “Journal of Pharmaceutical Innovation” In this study, the researchers developed and optimized a curcumin nanocrystal gel to enhance skin permeability, reporting improved dissolution properties and antiproliferative effects on cell lines, suggesting it as a promising topical delivery system.
40 citations
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December 2012 in “PLoS ONE” This study found that selective deletion of Ctip2 in epidermal keratinocytes in adult mice leads to atopic dermatitis-like inflammation and suggests Ctip2 plays a crucial role in skin barrier maintenance and inflammatory regulation.
January 2024 in “Animals” This study suggests that the transcription factors SP1 and KROX20 regulate CUX1 gene's effect on the proliferation of ovine dermal papilla cells in vitro.
2 citations
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August 2002 in “British Journal of Ophthalmology” This article discusses the potential of intralesional cidofovir as a treatment for SCC and reports no systemic toxicity, but highlights surgical excision as the most reliable curative option.
5 citations
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May 2020 in “Clinical Phytoscience” In this study, methanol extract of Cuscuta reflexa leaves significantly reduced blood glucose and improved insulin and liver function in alloxan-induced diabetic rats, indicating potential as an antidiabetic and organ-protective agent.