Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This commentary discusses the challenges of matrix effects in LC–MS analysis and introduces the concept of a matrix effect factor using stable isotopically labeled internal standards to improve analysis reliability.

This study developed a prototype device that suggests potential for diagnosing changes in hair quantity, diameter, and density, though formal clinical studies are needed to confirm these findings.

This study found that an ML model incorporating factors like Breslow thickness and age improved cutaneous malignant melanoma prognosis predictions compared to TNM staging, with a C-index of 80% versus 66.6% for TNM alone, suggesting ML's potential for personalized prognostication.

This review highlights the potential of PROTAC technology in drug discovery for previously undruggable targets, particularly in cancer therapy, while emphasizing the urgent need to discover more E3 ligase recruiters to optimize targeted protein degradation.

This observational study reviewed thyroid eye disease patients treated with teprotumumab at one center, reporting common side effects like fatigue and dry eye symptoms, with serious adverse events including two cases of blood clots and one pulmonary embolism.

This study found trichoscopy to be a highly sensitive, non-invasive method for diagnosing tinea capitis in children, which could be valuable in resource-limited settings lacking mycological culture facilities.

This study found that trichoblastomas and nodular basal cell carcinomas have similar cytokeratin expression patterns, indicating differentiation towards the outer root sheath epithelium.

This study found that multi-walled carbon nanotubes can enhance root hair growth in plants by influencing nitric oxide and ethylene signaling pathways, which highlights their potential application in agriculture.

This report suggests a possible association between temporal triangular alopecia and sebaceous nevus, and identifies a pinkish background as a new trichoscopic finding for TTA.

This analysis from Egyptian researchers identified common risk factors associated with chronic telogen effluvium in children, but it reports no new clinical results.

Direct-to-consumer teledermatology is not effectively reaching underserved populations due to language, technology, and insurance barriers.

This article discusses the diagnostic challenges between certain neonatal scalp conditions and highlights the potential of line-field confocal optical coherence tomography to provide detailed, non-invasive skin examination, without presenting new clinical findings.

This study found that dermatologists in an urban academic setting most frequently use topical corticosteroids, intralesional corticosteroids, and topical minoxidil for treating central centrifugal cicatricial alopecia, aligning with current literature recommendations on reducing inflammation.

This study explores the design of responsive drug carriers based on the tumor microenvironment to improve targeting and reduce side effects in cancer treatment, using a model of delivering curcumin with a responsive polymer carrier and evaluating potential errors due to cancer cell heterogeneity.

Ethinylestradiol/Chlormadinone Acetate is a safe and effective birth control pill that also helps regulate menstrual cycles, reduces period pain, and treats certain skin and hair conditions.

Mast cells may significantly contribute to central centrifugal cicatricial alopecia.

CEC levels may be a useful marker for predicting prostate cancer progression.

This case report describes a woman with trichotillomania who experienced marked improvement and hair regrowth after off-label onabotulinumtoxinA treatment.

In this study, improved hidden Markov algorithms based on Bayesian methods enhanced the resolution and segmentation accuracy of low-dose CT images significantly more than naive Bayesian methods.

This article reviews the clinical challenges in diagnosing tinea capitis due to its varying symptoms and reports no new clinical findings, emphasizing the need for careful differential diagnosis.

Traditional Chinese medications can cause skin reactions, and better testing and reporting are needed to identify allergens.

This case study reports a near-complete response of a proliferating trichilemmal tumor to neoadjuvant radiotherapy in a 79-year-old woman, highlighting radiotherapy's role in managing this condition when patients are unsuitable for surgery.

Congenital triangular alopecia can occur outside the typical fronto-temporal region.

This source reports that trastuzumab deruxtecan improves outcomes in HER2-positive and HER2-low metastatic breast cancer, emphasizing the need for careful adverse event monitoring, particularly for interstitial lung disease, and managing emetic risk to maximize benefits.

This study reported genetic mutations in trichilemmal carcinoma similar to those found in other skin cancers, including TP53 mutations associated with aggressive disease.

This article lists the clinically important interactions and skin reactions of several drugs and substances, including THA, FK506, tamoxifen, tamsulosin, tartrazine, tea tree oil, temazepam, and temozolomide, but provides no new clinical results.

This article describes a 10-month-old female with congenital smooth muscle hamartoma, highlighting the importance of differential diagnosis in congenital skin lesions due to potential malignancy risks.

This study investigated improving Finasteride's water solubility using trimethyl-β-cyclodextrin (TM-β-CD) and β-cyclodextrin (β-CD) as carriers, finding that β-CD improved Fin's cumulative release, while TM-β-CD enhanced its solubility, with computational data supporting these outcomes.

In this study, researchers found that β-catenin directly promotes TERT expression in stem and cancer cells by interacting with the Tert promoter, illustrating a mechanistic link between tumorigenesis and pluripotency.

This study found that administering tolerogenic dendritic cell-conditioned medium to dihydrotestosterone-treated mice promoted hair regrowth by modulating the follicular microenvironment, reducing pro-inflammatory cytokines, and activating key signaling pathways, highlighting its potential as a treatment for androgenetic alopecia.