The Application Progress of Tumor Microenvironment-Responsive Drug Carriers in Precision Chemotherapy

This article discusses the development of tumor microenvironment-responsive drug carriers to enhance precision chemotherapy by targeting the unique conditions of tumor cells, such as pH, REDOX substance concentration, and enzyme expression, to improve therapeutic targeting and minimize side effects like hair loss. It examines the design mechanisms of these carriers and evaluates the feasibility of targeted drug release using a pH-temperature responsive polymer carrier for curcumin delivery. The study also addresses the challenges posed by the high heterogeneity of cancer cells and explores the potential of artificial intelligence in creating personalized drug carriers based on the tumor microenvironment.