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Fat cells help recruit healing cells and build skin structure during wound healing.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Targeted cancer therapies often cause serious skin problems that need careful management.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

A patient with Alopecia Areata had complete hair regrowth after using the drug baricitinib.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

Sophora flavescens extract may help hair grow by affecting growth factors and blocking a hair-related enzyme.

A patient with alopecia areata regrew hair after taking tofacitinib and showed changes in certain blood and skin markers.

Blocking IL-12/IL-23p40 helped reverse severe hair loss in patients.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.