67 citations
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December 2013 in “Journal of Biological Chemistry” This review discusses the role of the enzyme Δ9-desaturase-1 in skin lipid regulation and whole-body energy balance in mice and reports no new experimental results.
June 2026 in “ACS Applied Materials & Interfaces” In this study, carbon dots derived from dandelion herb demonstrated significant antibacterial and biofilm-disrupting capabilities, promoting wound healing in a mouse model infected with S. aureus, while also showing excellent biocompatibility and the ability to modulate reactive oxygen species.
January 2010 in “Journal of Animal Science” This study demonstrated that transcutaneous vaccination via cyanoacrylate skin surface stripping effectively induced both CD4 and CD8 T cell responses in humans, offering a promising alternative to intramuscular injection.
14 citations
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February 2018 in “Psychoneuroendocrinology” This study found that male 5α-reductase 2 knockout mice showed deficits in social dominance behaviors and reduced dopamine receptor binding in a brain region related to social ranking.
2 citations
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June 2022 in “International Journal of Molecular Sciences” This study found variable outcomes in hair loss treatment with autologous cell-based therapy using DSC cells, with certain gene markers showing inconsistent correlations with treatment efficacy.
May 2024 in “British journal of dermatology/British journal of dermatology, Supplement” The researchers reported increased ubiquitination of proteins such as the insulin receptor in CYLD cutaneous syndrome skin tumors, suggesting that CYLD dysfunction may affect protein secretion and signaling processes.
June 2026 in “Journal of Investigative Dermatology” This study reported that the anti-γc antibody hC2 restored hair follicle homeostasis and suppressed hair loss in an AA-like mouse model by inhibiting autoreactive T-cell activity, suggesting that hC2 may offer a safer and more effective treatment for alopecia areata compared to current Jak inhibitors.
4 citations
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June 2025 in “Cochrane Database of Systematic Reviews” This Cochrane review found no clear superiority among treatments for central serous chorioretinopathy, with low-dose photodynamic therapy, supplements, and eplerenone showing slightly higher probabilities of improving visual acuity, but evidence remains uncertain due to biases and small study sizes.
4 citations
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August 2021 in “Pediatrics in review” This review explores disorders of sex development, emphasizing the need for a systematic, multidisciplinary approach and the benefits of genetic testing for better diagnosis and gender assignment planning, but it reports no new clinical findings.
April 2026 in “Scientific Reports” In this study, the proposed MSF-VMDNet, combining dual encoder networks with a multi-frequency domain mechanism, significantly outperformed existing methods in segmenting skin cancer tissues from histological slide images, achieving high accuracy with an MIoU of 95.37% and a Dice coefficient of 95.11%.
28 citations
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November 2018 in “American Journal of Medical Genetics Part A” This report describes a neurometabolic disorder linked to gain-of-function variants in the ODC1 gene, characterized by developmental delay, ectodermal abnormalities, and notable facial and neuroimaging features.
27 citations
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May 2007 in “Archives of dermatological research” In this study, alopecia areata patients treated with diphencyprone showed a significant increase in CD8 lymphocytes around hair bulbs, which may be associated with hair regrowth.
4 citations
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September 2024 in “Cell Reports” This study found that mice lacking the CXCR2 receptor regenerated tissue scarlessly in various injury models and that administering plasma or G-CSF from these mice to wild-type mice also reduced scarring, suggesting potential therapeutic strategies to improve human skin wound healing.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified that disrupting Mef2c in dermal papilla cells delays the early stages of hair cycle catagen in mice, revealing potential interactions with Sox18 in regulating hair growth.
12 citations
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September 2015 in “Drug Design Development and Therapy” This study found that the DOX derivative AD198 more effectively inhibited cell viability and induced apoptosis in canine cancer cell lines K9TCC and K9OSA compared to DOX in vitro.
8 citations
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June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study provides definitive evidence that a homozygous mutation in the DSC3 gene causes skin fragility and hypotrichosis in humans.
2 citations
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April 2022 in “Journal of Cosmetic Dermatology” This study found that de-saponinated Camellia seed cake extract promotes hair growth in vitro and in vivo by enhancing dermal papilla cell proliferation and modulating signaling pathways and growth factor expression.
61 citations
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January 2013 in “International Journal of Biological Macromolecules” This study found that applying both dehydrothermal treatment and carbodiimide crosslinking improved the mechanical properties of porcine acellular dermal matrix scaffolds without added cytotoxicity, suggesting potential applications in tissue engineering.
19 citations
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August 2023 in “Experimental & Molecular Medicine” This study found that the CXXC5 protein is overexpressed in diabetic foot ulcer tissues, suppressing wound healing, and that the small molecule KY19334 accelerated healing in diabetic mice by activating the Wnt/β-catenin pathway.
January 1982 in “Clinical Cosmetic and Investigational Dermatology” This case report describes a 54-year-old woman with familial dyskeratotic comedones who experienced slight improvement in her skin lesions after three months of treatment with topical retinoids and urea cream.
17 citations
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July 2014 in “Expert Opinion on Biological Therapy” This study concluded that the new subfractionation culturing method generates highly homogeneous adipose-derived stem cells with enhanced mitogenic, paracrine, and hair growth-promoting effects compared to traditional isolation methods.
This study reported that dandelion herb-derived carbon dots significantly enhanced wound healing in mice with Staphylococcus aureus infections, outperforming a commercial wound healing spray through their antibacterial and dual ROS-modulating capabilities.
3 citations
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December 2021 in “Frontiers in endocrinology” In this study, a novel DCAF17 gene mutation was identified in a Chinese family, suggesting a potential role in pancreatic β cell dysfunction and diabetes development in Woodhouse-Sakati syndrome.
This thesis found that desmoplakin mutations in cardiocutaneous syndrome are linked to dose-dependent disease severity and identified mechanisms by which KLHL24 mutations cause cardiomyopathy, with rescue experiments successfully preventing this phenotype in patient-derived heart tissues.
September 2022 in “Annals of medicine and surgery” This case report discusses the diagnostic challenges and management options for three siblings with 46, XY DSD due to type 2 5-α reductase deficiency, highlighting the genetic basis and impact on their quality of life.
March 1998 in “Journal of dermatological science” Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.
2 citations
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May 1985 in “Environmental Health Perspectives” This report examines the mechanisms by which TCDD affects human epidermal and carcinoma cells, aiming to create a risk assessment model for halogenated aromatic compounds, but presents no new clinical results.
67 citations
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September 2001 in “American Journal Of Pathology” This study found that overexpression of the enzyme ornithine decarboxylase in transgenic mice led to UVB-induced skin tumors, but this was prevented by the ODC inhibitor α-difluoromethylornithine.
July 2020 in “Research Square (Research Square)” This study found that a 3D co-culture of adipose-derived stem cells and endothelial colony forming cells restored stem cell properties and enhanced wound healing in a mouse model.
March 2024 in “Stem cell research & therapy” This study found that conditioned medium from human dental pulp stem cells (particularly under hypoxic conditions) improved keratinocyte survival and hair regrowth in a chemotherapy-induced alopecia mouse model and did not promote tumor growth, suggesting potential for safe therapeutic use.