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690-720 / 1000+ resultsresearch Clouston syndrome: A complete genotype–Phenotype correlation after four decades and six generations
This case report documents the first confirmed mutation-proved instance of Clouston syndrome in a large Chinese-Malaysian family, linked to the c.263C>T (A88V) mutation in the GJB6 gene, with no available treatment but highlighting the importance of genetic counseling.
research Board Certification
research Tolerability of hair cleansing conditioners: a double-blind randomized, controlled trial designed to evaluate consumer complaints to the U.S. Food and Drug Administration
In this double-blind, randomized controlled study, researchers found that Wen by Chaz Dean Sweet Almond Mint Cleansing Conditioner was similarly tolerated compared to three other hair cleansing conditioners and was significantly better tolerated than salicylic acid shampoo or baby shampoo in terms of skin reactions.
research Sphingolipid metabolism orchestrates establishment of the hair follicle stem cell compartment
This study found that deleting ceramide synthase 4 in skin epidermis stem cells disrupts hair follicle and skin barrier function, leading to immune responses similar to atopic dermatitis, due to imbalances in lipid composition affecting differentiation.
research Assessment of Cardiovascular Risk and Prevention of Cardiovascular Disease in Women with the Polycystic Ovary Syndrome: A Consensus Statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society
This review examines the relationship between polycystic ovary syndrome and cardiovascular disease risk, but reports no new clinical findings; the panel calls for guidelines to prevent CVD in this population.
research Emerging drugs and combination strategies for basal cell carcinoma
This review discusses Hedgehog inhibitors for basal cell carcinoma treatment, noting tumor regression during therapy but also challenges like muscle toxicity and potential resistance; it reports no new clinical findings.
research Liquid Chromatography-Mass Spectrometry Based Isotopic Abundance Ratio Analysis of the Consciousness Energy Healing Treated L-Cysteine
In this study, L-cysteine treated with the Trivedi Effect® showed significantly increased isotopic abundance ratios, which may enhance its stability and shelf-life.
research Cronkhite-Canada Syndrome: A Case Report
This case report describes a 40-year-old woman with Cronkhite-Canada Syndrome whose symptoms, including gastrointestinal issues and skin changes, improved significantly with corticosteroids, co-infection treatment, and nutritional counseling.
research Stem Cells in Nonmelanoma Skin Cancer
This review discusses the clonal or polyclonal nature of skin carcinomas and the stem cell origins of basal and squamous cell carcinomas but presents no new research findings.
research Steroid sulfatase inhibitors
This review discusses the development and potential therapeutic applications of steroid sulfatase inhibitors for hormone-dependent disorders and cognitive dysfunction, reporting no new clinical results.
research French administrative health care database (SNDS): The value of its enrichment
This report describes the enhancement of the French SNIIRAM/SNDS healthcare database through external data linkages, highlighting its potential use in medical research despite complexities in the integration process.
research Obsessive-compulsive skin disorders: a novel classification based on degree of insight
This article proposes a new classification, the Obsessive-Compulsive Insight Continuum, to help dermatologists better understand and diagnose skin disorders with obsessive-compulsive features.
research Integrated Model of Care for Polycystic Ovary Syndrome
This review discusses the challenges in diagnosing and managing polycystic ovary syndrome and highlights the need for an integrated, multidisciplinary healthcare model tailored to the diverse needs of women with PCOS; it reports no new clinical findings.
research Hair regrowth in 2 patients with recalcitrant central centrifugal cicatricial alopecia after use of topical metformin
This article discusses the staging of central centrifugal cicatricial alopecia in women of African descent and reports no new clinical results.
research Computer physics communications instructions to authors (third revision)
research Camellia japonica seed extract promotes hair growth by preventing dermal papilla cell senescence and activating hair follicle stem cells
This study found that Camellia japonica seed extract promotes hair growth by preventing premature cellular senescence and enhancing the activity of hair follicle stem cells in cases of pattern hair loss.
research Urological Drug Price Stewardship: Potential Cost Savings Based on the Mark Cuban Cost Plus Drug Company Model
This study suggests that adopting the Mark Cuban Cost Plus Drug Company model for purchasing urological medications could have saved Medicare about $1.29 billion in 2020.
research Cutaneous Two-Stage Chemical Carcinogenesis
This protocol details a method for inducing skin cancer in mice through chemical carcinogenesis, which studies cutaneous malignancies but does not report new findings.
research Clinical and trichoscopic features of early congenital syphilis: a single-center cross-sectional study
This study reported that trichoscopy can identify specific hair shaft abnormalities linked to increased serological activity, highlighting its use as a valuable non-invasive diagnostic tool in pediatric dermatology for neonates with ECS.
research 1457 CellutomeTM epidermal harvesting system and in vivo reflectance confocal microscopy as a novel wound healing assessment protocol
This study found that combining CelluTome system and RCM is a safe and effective protocol for evaluating wound healing responses in patients with epidermolysis bullosa.
research Central chorioretinopathy associated with topical use of minoxidil 2% for treatment of baldness
This article presents a case of central serous chorioretinopathy occurring after the use of topical minoxidil solution, but reports no clinical study findings.
research Enrichment and Characterization of Human Dermal Stem/Progenitor Cells by Intracellular Granularity
This study suggests that dermal stem/progenitor cells can be enriched by intracellular granularity and display high proliferation and differentiation potential in vitro, distinguishing them from other fibroblasts and progenitors.
research Expression of SPARC (secreted protein acidic rich in cysteine) throughout the hair cycle in rats
This study concludes that SPARC is likely a secondary response during the hair cycle's transitional phases, indicating tissue-remodeling processes similar to those in wound repair, rather than initiating these transitions.
research LO-009 Responsiveness of the CLASI to alopecia and mucous membrane involvement: a retrospective study of prospectively collected data
This study concluded that removing alopecia and mucous membrane components from the CLASI-A score limits the ability to capture crucial clinical information about cutaneous lupus erythematosus activity, recommending their retention.
research DICENTRIC CHROMOSOME 14;18 PLUS TWO ADDITIONAL CNVs IN A GIRL WITH MICROFORM HOLOPROSENCEPHALY AND TURNER STIGMATA
This case report highlights the use of microarray analysis to identify cryptic chromosomal rearrangements in a young woman with intellectual disability and multiple congenital anomalies.
research Fibroproliferative genes are preferentially expressed in central centrifugal cicatricial alopecia
This study identified upregulation of genes linked to fibroproliferative disorders, such as platelet-derived growth factor and collagen genes, in patients with central centrifugal cicatricial alopecia, suggesting potential therapeutic targets.
research Bilayer Silk Fibroin/Sodium Alginate Scaffold Delivered hUC-MSCs to Enhance Skin Scarless Healing and Hair Follicle Regeneration with the IRE1/XBP1 Pathway Inhibition
This study found that a silk fibroin/sodium alginate scaffold effectively delivers human umbilical mesenchymal stem cells to promote scarless wound healing and hair follicle regeneration in vivo by inducing specific cellular processes and mitigating endoplasmic reticulum stress.
research 175 Understanding immune privilege in an inducible mouse model of primary cicatrcial alopecia
This study reports that CD200R expression is significantly reduced in an experimental mouse model of scarring alopecia, suggesting a potential role for this pathway in immune regulation and hair follicle protection.
research Molecular heterogeneity of quiescent melanocyte stem cells revealed by single‐cell RNA‐sequencing
This study explored the diversity of melanocyte stem cell subpopulations in the hair follicles of adult female mice and identified novel groups with distinct immune privilege regulation, suggesting a heterogeneous landscape that future research should consider.