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Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Gut health affects skin diseases, and probiotics might help.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Both treatments for pemphigus foliaceus in dogs are effective, but combination therapy has more side effects.

Dogs with generalized discoid lupus erythematosus have similar symptoms to humans and need continuous treatment.

The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.

The document is a detailed guide on skin conditions and treatments for dermatologists.

Testosterone therapy can help improve sexual function, mood, and bone density in women with low androgen levels, but more research is needed on long-term safety.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Shift work disrupts the body's natural clock, leading to health problems.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

The document concludes that diagnosing and treating Congenital Adrenal Hyperplasia is complex and requires a team approach due to its effects on the skin and other symptoms.

Herbal remedies can cause adverse effects and need more safety research.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

Disrupting natural body clocks increases the risk of developing type 2 diabetes.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Early recognition and aggressive treatment can significantly improve rare ANA-negative lupus with heart and skin issues.

Dermoscopy helps diagnose and monitor treatment for hair loss from scarring conditions like discoid lupus and lichen planopilaris.

The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.

Meis2 is essential for touch sensation and nerve function in mice.

Many hospitalized children with COVID-19 had skin, mouth, or nail changes, with skin rashes being common.

COVID-19 may lead to severe skin necrosis without clear underlying causes, as seen in a diabetic patient who required leg amputation.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Hair proteins in preschool children and their mothers could indicate developmental changes and health status.

Men with higher androgen levels may have severe COVID-19 symptoms, but those on antiandrogen therapy are less likely to contract the virus and have milder symptoms. Anti-androgen drugs could potentially treat COVID-19, but more research is needed.

Natural products may help treat skin inflammation from abnormal adrenal hormones.