research Epidermal Differentiation Complex: A Review on Its Epigenetic Regulation and Potential Drug Targets
Understanding how EDC genes are regulated can help develop better drugs for skin diseases.
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research Understanding the Effect on Hair Fibers of Coloring and Bleaching Formulations Using High Pressure Differential Scanning Calorimetry
Hair coloring and bleaching can permanently break down hair protein and temporarily change its properties.
research Extraction of Keratin from Human Hair Waste for Copolymerization with Nitrile Butadiene Rubber
Human hair keratin mixed with rubber slightly improves its strength and biodegradability.
research Alkylating Agents: History and Effects in Chemotherapy
Alkylating agents can kill cancer cells but may cause skin and allergic reactions.
research In Search of Decoding the Syntax of the Bioelements in Human Hair: A Critical Overview
Hair analysis can show nutritional status and environmental exposure, with phosphorus being very stable in hair and differences found based on gender and conditions like depression and autism.
research Drug Repurposing Against KRAS Mutant G12C: A Machine Learning, Molecular Docking, and Molecular Dynamics Study
Afatinib, neratinib, and zanubrutinib could be effective against KRASG12C-mutant tumors.
research Regulation of Androgen Receptor and 5α-Reductase in the Skin of Normal and Hirsute Women
The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.
research Physicochemical Characterization of Finasteride: PEG 6000 and Finasteride: Kollidon K25 Solid Dispersions, and Finasteride: Beta-Cyclodextrin Inclusion Complexes
Finasteride's solubility and bioavailability improved by forming solid dispersions and inclusion complexes.
research Attempted Construction of Minoxidil: Carboxylic Acid Cocrystals; 7 Salts and 1 Cocrystal Resulted
Made 8 minoxidil samples; 1 cocrystal, 7 salts formed.
research The Structure of the Amorphous Matrix of Keratins
Human hair keratin fibers have a detailed nano-scale structure that changes with different conditions.
research Injectable Self-Healing Ceria-Based Nanocomposite Hydrogel with ROS-Scavenging Activity for Skin Wound Repair
The hydrogel speeds up skin wound healing and helps regenerate tissue.
research Experimental, Molecular Docking Investigations and Bioavailability Study on the Inclusion Complexes of Finasteride and Cyclodextrins
Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.
research Exogenous Factors in Hair Disorders
Outside factors like grooming, chemicals, and the environment can damage hair and cause disorders.
research Preparing the Hair Follicle Canal for Hair Shaft Emergence
A specific type of skin cell creates an opening for hair to grow out, and problems with this process can lead to skin conditions.
research Repair of Damaged Hair Protein Fiber by Jointly Using Transglutaminase and Keratin
Using an enzyme and keratin treatment can significantly repair and strengthen damaged hair.
research Hair Growth Promoting Activity of Discarded Biocomposite Keratin Extract
Keratin extract from human hair was found to promote hair growth in mice.
research Discussion: Themes in the Molecular Structure of Hair
Keratin proteins are crucial for hair structure and strength.
research Dual Growth Factor Releasing Multi-Functional Nanofibers for Wound Healing
The nanofibers with two growth factors improved wound healing by supporting structure, preventing infection, and aiding tissue growth.
research Severe Cutaneous Adverse Reactions to Drugs
Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.
research Phenotypic Variation in Biotinidase Deficiency
Biotinidase deficiency has various symptoms and can be treated with biotin supplements.
research Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP-Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor
Finasteride effectively blocks enzyme causing male pattern baldness.
research Tregs: Where We Are and What Comes Next?
The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
research In Vivo Immunological Toxicity in Mice of Carbon Nanotubes with Impurities
Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.
research Multidomain Peptide Hydrogel Accelerates Healing of Full-Thickness Wounds in Diabetic Mice
MDP hydrogel heals wounds faster and better than other treatments in diabetic mice.
research The Endocannabinoid System of the Skin: A Potential Approach for the Treatment of Skin Disorders
Targeting the skin's endocannabinoid system could help treat skin disorders.
research Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders
S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
research Hair Coloring, Permanent Styling, and Hair Structure
Frequent hair coloring and styling can damage hair and cause breakage or loss.
research Finasteride: A Slow-Binding 5-Alpha-Reductase Inhibitor
Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.
research Hair and Scalp Disorders in Ethnic Populations
Different hair care practices and conditions affect African American hair and scalp health, requiring specialized knowledge for treatment.
research Diet and Pemphigus
Avoiding certain nutrients and drugs may help manage pemphigus.